George E. Christodoulakos,1 Irene V. Lambrinoudaki,1 Demetrios A. Rizos,2 Andreas Alexandrou,3 Apostolos V. Kountouris,1 George C. Creatsas1 12nd Department of Obstetrics and Gynecology, 2Hormonal and Biochemical Laboratory, "Aretaieion" Hospital, Athens University Medical School, 32nd Department of Surgery, "Laikon" Hospital, Athens University Medical School, Athens, Greece Abstract OBJECTIVE: The determinants of serum homocysteine in healthy postmenopausal Read More
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Polycystic Ovary Syndrome: The influence of environmental and genetic factors
Evanthia Diamanti-Kandarakis,1 Christina Piperi,2 Georgia Argyrakopoulou,1 Jiovanna Spina,1 Lambrini Papanastasiou,1 Angeliki Bergiele,1 Dimitrios Panidis3 1First Department of Internal Medicine, Endocrine Section, 2Laboratory of Biological Chemistry, Athens University Medical School, Athens, 3Division of Endocrinology and Human Reproduction, 2nd Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Thessaloniki, Greece Abstract Polycystic ovary syndrome (PCOS) is a Read More
Depression and Osteoporosis in Men: Association or Casual Link?
Ioannis Ilias,1 Salvatore Alesci,2 Philip W. Gold,2 George P. Chrousos3 1Department of Pharmacology, Patras University Medical School, Rion-Patras, Greece, 2Clinical Neuroendocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA, 31st Department of Pediatrics, Athens University Medical School, “Agia Sophia” Children’s Hospital, Athens, Greece Abstract The longer life expectancy of women Read More
Pycnodysostosis: Toulouse-Lautrec’s and Aesop’s disease?
Christos S. Bartsocas Department of Pediatrics, Faculty of Nursing, University of Athens, Athens, Greece INTRODUCTIONAmong the several causes of short stature is pycnodysostosis, also known as “Toulouse-Lautrec’s disease”.1,2 Robert Weismann-Netter is credited with the first description of the disorder which later became known as pycnodysostosis.3 Only a few, however, know that pycnodysostosis was also p¦ssibly Read More
Primary malignant fibrous histiocytoma on the thyroid
Fotini Malandrinou1, Sofia Tseleni-Balafouta2, Nicolaos Kakaviatos2, Panagiotis Singhellakis1 1Department of Endocrinology “St. Savvas” Hospital, Athens – Greece, 2Department of Anatomic Pathology and 2nd Surgical Clinic, Athens University Medical School, Athens – Greece Abstract A 42-year old white female with a primary Malignant Fibrous Histiocytoma (MFH) is described. The patient was examined for a “cold” nodule Read More
Testicular leydig cell tumor presenting as primary infertility
Athina Markou1, Justin Vale2, Bhumita Vadgama1, Marjori Walker2, Stephen Franks1 1Department of Reproductive Science and Medicine, Imperial College Faculty of Medicine, 2St Mary’s Hospital, London Abstract A 29-year old male and his wife presented with an 18 month history of primary infertility. History and initial investigations suggested no major female pathologic component but a semen Read More
Secular growth changes in the Hellenic population in the twentieth century
Anastasios Papadimitriou1, Dimitrios Chiotis2, Georgios Tsiftis2, Maria Hatzisimeon2, Maria Maniati2, Xenofon Krikos2, Anastasia Tzonou3, Catherine Dacou-Voutetakis2 1Penteli Children’s Hospital, 2Endocrine Unit, First Dept of Pediatrics, Athens University Medical School, 3Dept of Hygiene Epidemiology, Athens University Medical School, Athens, Greece Download PDF Address correspondence and requests for reprints to: C. Dacou-Voutetakis, Agia Sophia Children’s Hosp. Goudi Read More
Continuous combined replacement therapy in postmenopausal women: effect on plasma lipoproteins, bone mass and the endometrium
Odysseas Gregoriou,George Christodoulakos, Charalambos Siristatidis, Socrates Conidaris, Evangelia Kouskouni, George Creatsas 2nd Department of Obstetrics and Gynaecology, Aretaieion Hospital, University of Athens Medical School, Athens, Greece Abstract Objective: The purpose of this study was to examine the effects of Hormone Replacement Therapy (HRT) on plasma lipoprotein levels, bone mass and the endometrium. Methods: Thirty healthy Read More
Glucocortidoid sensitivity assessed in peripheral blood cells do not correlate with the feedback sensitivity of the hypothalamo-pituitary adrenal AXIS
Dimitra Vasiliadi1, Yannis Gratsias2, Stylianos Tsagarakis1, Eythimia Botoula1, Panagiotis Trivizas1, Nick Thalassinos1, Paraskevi Moutsatsou2 1Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital and 2Department of Biochemistry, Athens University Medical School Abstract Glucocorticoids (GC) affect virtually all organ systems, acting mainly via the glucocorticoid receptor (GR). The immune system is the best characterized tissue for assessing Read More
Structure-function relationships of glycoprotein hormones; lessons from mutations and polymorphisms of the thyrotrophin and gonadotrophin subunit genes
Maria Alevizaki1, Ilpo Huhtaniemi2 1Endocrine Unit, Department of Medical Therapeutics, Athens University School of Medicine, Athens, Greece, and 2Institute of Reproductive and Developmental Biology, Imperial College Medical Faculty, London, U.K. Abstract The pituitary glycoprotein hormones thyrotrophin (thyroid-stimulating hormone, TSH), lutrophin (luteinising hormone, LH) and follitrophin (follicle-stimulating hormone, FSH), as well as the placental choriongonadotrophin (human Read More