Adrenal venous sampling as a diagnostic procedure for primary hyperaldosteronism: experience from a tertiary referral centre

Victoria Salem, Thomas G. Hopkins, Heba El-Gayar, Sagen Zac-Varghese, Anthony P. Goldstone, Jeannie F. Todd, Waljit Dhillo, Benjamin C.T. Field, Niamh Martin, Emma Hatfield, Mandy Donaldson, Fausto Palazzo, Karim Meeran, James Jackson, Tricia Tan

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CONTEXT: Adrenal vein sampling (AVS) is recommended in all patients with hyperaldosteronism to whom surgery would be offered if the results indicated unilateral hypersecretion. OBJECTIVE: To assess the performance of AVS against radiological findings …

Sleep quality in patients with primary aldosteronism

Franziska M. Hanusch, Evelyn Fischer, Katharina Lang, Sven Diederich, Stephan Endres, Bruno Allolio, Felix Beuschlein, Martin Reincke, Marcus Quinkler, for the participants of the German Conn’s Registry

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OBJECTIVE: In subjects at high risk for sleep apnea (SA), aldosterone concentrations correlate with severity of SA and primary aldosteronism (PA) is very often diagnosed. Patients with PA show a high prevalence of SA. Treatment of PA either by adrenalectomy (ADX) or mineralocorticoid receptor (MR) blockade is thought to abolish …

A unique case of a benign adrenocortical tumor with triple secretion of cortisol, androgens, and aldosterone. Development of multiple sclerosis after surgical removal of the tumor

Athina Markou, Kaity Tsigou, Dimitrios Papadogias, Kostas Kossyvakis, Kyriakos Vamvakidis, Theodora Kounadi, George Piaditis

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We present a 39-year old female with a benign adrenal tumor characterized by autonomous secretion of cortisol, androgens, and aldosterone. The patient presented with a 4-year history of hypertension and severe hirsutism. Baseline investigations revealed elevated testosterone, androstendione, and 17OH progesterone with normal levels of dehydroepiandrosterone sulfate…