Medical treatment of hypercalcaemia

Polyzois Makras, Socrates E. Papapoulos

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Hypercalcaemia results from the failure of renal calcium excretion to compensate increased influx of calcium into the circulation from the intestine, the kidneys and the skeleton. Hypercalcaemia is a common metabolic abnormality of varying severity …

Bisphosphonate-associated adverse events

Peter D. Papapetrou

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The adverse events of the nitrogen-containing bisphosphonates are reviewed. Oral bisphosphonates (alendronate, risedronate and ibandronate), mainly used for the treatment of osteoporosis, have been associated with adverse events from the upper gastrointestinal tract …

Diagnosis of pheochromocytoma with special emphasis on MEN2 syndrome

Karel Pacak, Graeme Eisenhofer, Ioannis Ilias

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Pheochromocytomas/paragangliomas(PHEOs/PGLs) are rare but treacherous catecholamine-producing tumors which, if overlooked or improperly treated, will almost invariably prove fatal. Patients with MEN2 PHEOs have a high incidence of paroxysmal attacks …

The insulin-like growth factor-I (IGF-I) generation test as an indicator of growth hormone status

Bessie E. Spiliotis, Theodore K. Alexandrides, Christoforos Karystianos, Pavlos Vassilakos, Zvi Zadik, Nikoleta M. Nikolakopoulou, George Nikiforidis, Nicholas G Beratis

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OBJECTIVE: The aim of the study was to evaluate the IGF-I generation test (IGF-I gen) as a possible indirect test of Growth Hormone (GH) secretory status. METHODS: Sixty-five GH deficient (GHD 1 and 2) and 86 control children were studied …

Physical training in patients on hemodialysis has a beneficial effect on the levels of eicosanoid hormone-like substances

Ioannis Karamouzis, Dimitrios Grekas, Michael Karamouzis, Konstantinos Kallaras, Vassiliki Stergiou-Michailidou, Evangelia Kouidi, Asterios Deligiannis, Norma Vavatsi-Christaki

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OBJECTIVE:The aim of this study was to evaluate the changes in the levels of vasoactive eicosanoid hormone-like substances PGE2, PGI2 and TXA2 in hemodialysis (HD)patients who were following a long-term physical training program …

Laparoscopic sleeve gastrectomy in morbidly obese patients. Technique and short term results

Andreas Kiriakopoulos, Christos Varounis, Dimitrios Tsakayannis, Dimitrios Linos

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Objective: To evaluate the efficacy of Laparoscopic Sleeve Gastrectomy (LSG) as a definitive procedure for morbidly obese patients. Design: This constitutes a prospective study carried out in a tertiary care private hospital and included 15 morbidly obese patients who underwent LSG …

Supernumerary ectopic parathyroid glands. Persistent hyperparathyroidism due to mediastinal parathyroid adenoma localized by preoperative single photon emission computed tomography and intraoperative gamma probe application

Mehmet Uludag, Adnan Isgor, Gürkan Yetkin, Murat Atay, Abut Kebudi, Ismail Akgun

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Ectopic and/or supernumerary parathyroid glands are a major cause of persistent and recurrent Hyperparathyroidism (HPT). For this reason, it is widely accepted that preoperative localization should be performed to improve the surgical results in patients with persistent or recurrent HPT …