The role of estrogens in cardiovascular disease in the aftermath of clinical trials

Lambrini Gouva, Agathocles Tsatsoulis

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The effects of estrogens on reproductive tissues and climacteric symptoms are unambiguous. However, their effects on other tissues and, in particular, the cardiovascular system remain controversial. In general, premenopausal women are protected from coronary heart disease (CHD) compared with aged-matched men but this `female protection’ appears to be lost after menopause, suggesting beneficial effects of female sex hormones on the cardiovascular system…

Bisphenol-A: a new diabetogenic factor?

Paloma Alonso-Magdalena, Ana Belιn Ropero, Sergi Soriano, Ivan Quesada, Angel Nadal

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The aim of this review was to analyze the potential effects of environmental chemicals on homeostatic control related to glycemia and energy balance. Many of the environmental chemicals can mimic or interfere with the action of hormones and are generally referred to as “endocrine disruptors” …