George E. Christodoulakos, Irene V. Lambrinoudaki, Demetrios A. Rizos, Andreas Alexandrou, Apostolos V. Kountouris, George C. Creatsas
OBJECTIVE: The determinants of serum homocysteine in healthy postmenopausal women remain uncertain. The aim of this study was the assessment of the association of endogenous sex steroids with serum homocysteine levels in healthy postmenopausal women not on hormone therapy…
Leonidas H Duntas, Constantinos Parisis
The aim of this review is to provide an update on drug abuse by athletes, their mode of action and the technical difficulties of detection. The most common doping agents are the anabolic steroids (AS), testosterone derivatives modified to take advantage of the anabolic rather than the androgenic properties of the hormone…
Charilaos Tsolakis, Paraskevi Xekouki, Socratis Kaloupsis, Dimitrios Karas, Dimosthenis Messinis, George Vagenas, Athanasios Dessypris
The purpose of this study was two fold a) to determine the levels of hormonal parameters which are related to growth and sexual maturation (T, SHBG, FAI, GH) in 66 pre-pubertal and early-pubertal boys (11-13 years old) who systematically engage in individual and team sports activities of endurance, strength, speed and skill, respectively …
Menelaos L. Batrinos
Male pattern baldness, scientifically known as androgenetic alopecia (AGA), is a very common condition, universally prevalent, which progresses with aging. The loss of scalp hair of any degree both in men and women is a cause of considerable psychological distress …
Simon Chang, Anne Skakkebæk, Claus Højbjerg Gravholt
Klinefelter syndrome (KS), though described more than 70 years ago, still imposes significant diagnostic challenges. Based on data from epidemiological studies, KS is associated with increased morbidity and mortality. Although the pathophysiology and etiology behind these observations are as yet not well understood …
Evangelia Tantalaki, Christina Piperi, Sarantis Livadas, Anastasios Kollias, Christos Adamopoulos, Aikaterini Koulouri, Charikleia Christakou, Evanthia Diamanti-Kandarakis
OBJECTIVE: To investigate the impact of dietary intervention on Advanced Glycation End products (AGEs) intake on the hormonal and metabolic profile in women with polycystic ovary syndrome (PCOS). METHODS: After baseline evaluation, 23 women with PCOS …
Ilpo Huhtaniemi, Juuso I. Mäkinen, Antti Perheentupa, Olli T. Raitakari
Interest has arisen during the last 10 years as to the possible connection between the age-related decline in androgen production and symptoms of ageing in men. A new ageing-related syndrome with several descriptive names …
Stergios A. Polyzos, Jannis Kountouras, Agathocles Tsatsoulis, Efthimia Zafeiriadou, Evangelia Katsiki, Kalliopi Patsiaoura, Christos Zavos, Vasiliki V. Anastasiadou, Aristidis Slavakis
OBJECTIVE: The evaluation of serum sex steroids and sex hormone-binding globulin (SHBG) levels in postmenopausal women with nonalcoholic fatty liver disease (NAFLD) and their association to the disease severity. DESIGN: Twenty-two postmenopausal women with biopsy-proven NAFLD …
Giovanni Corona, Silvia Bianchini, Alessandra Sforza, Linda Vignozzi, Mario Maggi
There is evidence demonstrating that sexual complaints represent the most specific symptoms associated with late onset hypogonadism, while central obesity is the most specific sign. In obese men, hypogonadism can further worsen the metabolic profile and increase abdominal fat …
Pavlina D. Avgoustinaki, Effrosyni Mitsopoulou, Gregorios Chlouverakis, Theoni Triantafillou, Maria Venihaki, Sofia Koukouli, Andrew N. Margioris
OBJECTIVE: Sex steroids affect human behavior. The aim of the present study was to determine the associations, if any, between the circulating levels of gonadal and adrenal sex steroids in the mid luteal phase (21st day of a normal menstrual cycle, MC) of young professional …
Aleksander Giwercman, Yvonne Lundberg Giwercman
An ever-increasing proportion of young males treated for cancer are cured. Therefore, one of the major challenges of modern Clinical Oncology is to ensure good quality of life. Cancer disease per se as well as cancer treatment may have a negative impact on androgen production, thereby leading to subclinical or clinically overt hypogonadism …
George A. Kanakis, Dimitrios D. Goulis
Despite the variety of available female contraceptive methods, many pregnancies (~50%) are still undesired. Many men (>60%) want to participate equally with their partner in family planning; however, male contraceptive methods (MCMs) account for only 14% of those used worldwide and no pharmaceutical MCM is available so far …
Nikolaos E. Koundourakis, Nikolaos Androulakis, Eirini C. Spyridaki, Elias Castanas, Niki Malliaraki, Christos Tsatsanis, Andrew N. Margioris
OBJECTIVE: To examine the effects of three seasonal training programs, largely different in strength volume, on androgen levels and performance parameters in soccer players. DESIGN: Sixty-seven soccer players, members of three different professional teams, participated in the study …
Anastasia Sfikakis, Pothitos M. Pitychoutis, Aikaterini Tsouma, Ioanna Messari, Zeta Papadopoulou-Daifoti
OBJECTIVE: To examine the impact of circulating testosterone (T) and the T/Estradiol (T/Ediol) ratio on chronic stress-induced changes of adrenal and hippocampal weight during proestrus (PE) and estrus (E) in female rats. DESIGN: Stress was composed of repeated vaginal smear screening (VSS) and measured by the emotional reactivity score …