Artemis Karkanaki, Christos Vosnakis, Dimitrios Panidis
Anti-Müllerian hormone (AMH) is a homodimeric glycoprotein, a member of the transforming growth factor-β superfamily. Over the last decade, a large number of studies examining the multiple roles of AMH have been published. AMH levels accurately reflect the ovarian follicular reserve and could, therefore …
Nikolaos D. Roupas, Neoklis A. Georgopoulos
OBJECTIVE: To highlight the recent developments in the field of menstrual function in sports and to provide an overview of our current understanding in regard to the pathophysiology, evaluation and management strategies of exercise-related reproductive dysfunction …
Foteini Economidou, Evangelia Douka, Marinella Tzanela, Serafeim Nanas, Anastasia Kotanidou
The metabolic support of the critically ill patient is a relatively new target of active research and little is as yet known about the effects of critical illness on metabolism. The nonthyroidal illness syndrome, also known as the low T3 syndrome or euthyroid sick syndrome, describes a condition characterized by abnormal thyroid function …
Anna-Maria Touvra, Konstantinos A. Volaklis, Apostolos T. Spassis, Christos E. Zois, Helen T. Douda, Kalliopi Kotsa, Savvas P. Tokmakidis
OBJECTIVE: The aim of the present study was to examine the effects of a combined strength and aerobic training program on pro- and anti-inflammatory cytokines and transforming growth factor-β1 in patients with type 2 diabetes. DESIGN: Ten patients with type 2 diabetes, aged 55.5 (5) years [median (IQR)] participated in a supervised systematic exercise training program …
Panagiotis N. Singhellakis, Fotini Ch. Malandrinou, Catherine J. Psarrou, Alexandra M. Danelli, Sotirios D. Tsalavoutas, Evangelia S. Constandellou
OBJECTIVE: The precise incidence of vitamin D deficiency is not known, primarily because there is no consensus on the optimal levels of serum 25(OH)Vitamin D. The aim of the present study was to determine the incidence of vitamin D deficiency in a large group of normal adult volunteers residing in a typical temperate region …
Paola Travaglino, Cristina Meazza, Sara Pagani, Giada Biddeci, Mauro Bozzola
OBJECTIVE: The aim of this study was to investigate whether a secular trend in growth occurred during the last century in Pygmies from Cameroon (West Pygmies) and in Bantu rural farmers, the latter being studied to serve as controls. DESIGN: The evolution in height of West Pygmies and Bantu farmers from 1911 to 2006 was evaluated using data from the literature …
Vana Spoulou, Christina Kanaka-Gantenbein, Irini Bathrellou, Stefano Mora, Glyceria Mostrou, Lambros Sidossis, George Chrousos, Maria Theodoridou
OBJECTIVE: Few studies have thus far assessed body composition by dual energy X-ray absorptrometry (DXA) in children with HIV, primarily because reference data for normally growing children and adolescents are not available. Our study aimed at evaluating body composition in children with HIV and their relatiοn to serum lipids and glucose homeostasis …
Amir H. Sam, Tricia Tan, Karim Meeran
Patients with acromegaly have characteristic clinical features caused by soft tissue overgrowth. The most common cause of acromegaly is a growth hormone-secreting adenoma of the anterior pituitary. Both somatic and metabolic features of acromegaly are due to excess growth hormone (GH) secretion and high serum concentrations …
Olga Moshkin, Luis V. Syro, Bernd W. Scheithauer, Leon D. Ortiz, Camilo E. Fadul, Humberto Uribe, Ricardo Gonzalez, Michael Cusimano, Eva Horvath, Fabio Rotondo, Kalman Kovacs
Temozolomide (TMZ) has recently been recommended as a novel approach in the management of aggressive pituitary tumors. Herein, we present the case of a 43-year-old man with a 20-year history of silent subtype 2 pituitary corticotroph adenoma. Nine surgical resections and radiotherapy had failed to provide a cure. Morphological evaluation of the tumor revealed …