Advanced glycation end products and diabetic complications: A General overview

Melpomeni Peppa, Helen Vlassara

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Diabetes mellitus, especially type 2 diabetes, is increasing at an alarming rate and is considered as one of the main threats to human health in the 21st century, in both developed and developing nations.1
More than 150 million people currently have diabetes, and twice that number is at high risk of developing diabetes in the next 5-10 years …

Muscle strength and bone in healthy women: effect of age and gonadal status

Cristiana Cipriani, Elisabetta Romagnoli, Vincenzo Carnevale, Ida Raso, Addolorata Scarpiello, Maurizio Angelozzi, Andrea Tancredi, Stefania Russo, Federica De Lucia, Jessica Pepe, Salvatore Minisola

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OBJECTIVE: The aim of this work was to examine the effects of age and menopause on muscle strength and on the muscle-bone interaction. DESIGN: One hundred ninety-four healthy women (mean age 49.8 ± 12.6 SD years) were assessed …

Associations of menstrual cycle irregularities with age, obesity and phenotype in patients with polycystic ovary syndrome

Dimitrios Panidis, Konstantinos Tziomalos, Efstathios Papadakis, Panagiotis Chatzis, Eleni A. Kandaraki, Elena A. Tsourdi, Djuro Macut, Jelica Bjekic-Macut, Apostolos Marthopoulos, Ilias Katsikis

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OBJECTIVE: Limited data suggest that menstrual cycle abnormalities are more pronounced in younger and more obese patients with polycystic ovary syndrome (PCOS). We aimed to evaluate the association between menstrual cycle pattern and age, obesity and PCOS phenotype in a large population of women with PCOS …