Tag: Cortisol
Exercise and the Stress System
George Mastorakos, Maria Pavlatou, Evanthia Diamanti-Kandarakis, George P. Chrousos
Exercise represents a physical stress that challenges homeostasis. In response to this stressor, autonomic nervous system and the hypothalamic-pituitary-adrenal axis are known to react and to participate in the maintenance of homeostasis. This includes elevation of cortisol and cathecholamines in plasma. However, sustained physical conditioning in highly trained athletes is associated…
Intramuscular administration of ACTH1-24 vs. 24-hour blood sampling in the assessment of adrenocortical function
Salvatore Alesci, Ioannis Ilias, Emmanuil Souvatzoglou, Alan G. Harris, Philip W. Gold, Alejandro R. Ayala, George P. Chrousos
The standard intravenous short Synacthen® test (SSST) has long been accepted as one of the most reliable diagnostic tests of adrenocortical insufficiency. Intramuscular (i.m.) administration of ACTH obviates the need of venous cannulation and can be used as an alternative to the intravenous test …
Stimulation of the hypothalamic-pituitary-adrenal axis with corticotropin releasing hormone in patients with psoriasis
Evangelos Karanikas, Faidon Harsoulis, Ioannis Giouzepas, Ioannis Griveas
OBJECTIVE: Psychocutaneous diseases constitute a large proportion of psychosomatic disorders, with psoriasis being one of the most typical cases. Though alteration of Hypothalamic-Pituitary-Adrenal (HPA) axis function has been suggested as underlying several psychiatric disorders and psychosomatic diseases, there is little evidence of reduced response of the HPA axis in psoriasis after psychosocially …