Antje Körner, Susann Blüher, Thomas Kapellen, Ante Garten, Jürgen Klammt, Jürgen Kratzsch, Wieland Kiess
Body weight is regulated by a feedback loop in which peripheral signals report nutritional information to an integratory center in the brain. The cloning of the ob gene is consistent with this concept and suggests that body fat content in adult rodents is regulated by a negative feedback loop centered in the hypothalamus…
Sofia Kitsiou-Tzeli, Aggeliki Kolialexi, Ariadni Mavrou
Microdeletions, translocations or other rearrangements of chromosomal region 22q11.2 have been reported in association with >80 different birth defects and malformations occurring in many combinations and with widely differing severity…
Eirini Papageorgiou, Ioanna Kotsioni, Athena Linos
This issue hosts an article that discusses the application of Data mining techniques to the treatment of infertile men with azoospermia, and compares this procedure of categorisation into groups with the corresponding clinical categorisation…
Kalliopi Pazaitou-Panayiotou, Athina Kaprara, Maria Boudina, Eleni Georgiou, Apostolos Drimonitis, Ekaterini Raptou, Grammati Galaktidou, Iraklis Vainas
OBJECTIVE: To define clinical presentation, surgical complications, follow-up characteristics, and survival of 23 children and adolescents with thyroid carcinoma. DESIGN: Retrospective analysis of data of 23 children and adolescents with thyroid carcinoma cared for in the Theagenion Cancer Hospital, Thessaloniki…
Themistoklis Mikos, Konstantinos Pantazis, Dimitrios G. Goulis, Nikolaos Maglaveras, John N. Bontis, John Papadimas
OBJECTIVE: Data Mining is a relatively new field of Medical Informatics. The aim of this study was to compare Data Mining diagnosis with clinical diagnosis by applying a Data Miner (DM) to a clinical dataset of infertile men with azoospermia. DESIGN: One hundred and forty-seven azoospermic men were clinically classified into four groups …
Athina Markou, Kaity Tsigou, Dimitrios Papadogias, Kostas Kossyvakis, Kyriakos Vamvakidis, Theodora Kounadi, George Piaditis
We present a 39-year old female with a benign adrenal tumor characterized by autonomous secretion of cortisol, androgens, and aldosterone. The patient presented with a 4-year history of hypertension and severe hirsutism. Baseline investigations revealed elevated testosterone, androstendione, and 17OH progesterone with normal levels of dehydroepiandrosterone sulfate…
Eleni Kousta, Konstantinos Konstantinidis, Christina Michalakis, George E. Theodoropoulos, Michalis Vorias, Michalis Georgiou, George Sambalis
Ectopic thyroid tissue in the lower neck with a coexisting normally located multinodular goiter is a rare entity. We present a 27-year old asymptomatic woman with a recent history of a painless mass in the left side of her lower neck. Thyroid function tests were normal. An ultrasound of her neck showed a multinodular goiter and a 3.4 cm solid mass in the left lower cervical area…