George P. Chrousos, Achille Gravanis, Andrew (Andy) N. Margioris
Wylie Walker Vale, Jr. was born in Houston, Texas, on July 3, 1941. While still in high school, he met and fell in love with his wife Betty to whom he was married for over 40 years. Wylie earned his bachelor’s degree in Biology …
Adeeb Shehzad, Waqas Iqbal, Omer Shehzad, Young Sup Lee
Adiponectin is a white and brown adipose tissue hormone, also known as gelatin-binding protein-28 (GBP28), AdipoQ, adipocyte complement-related protein (ACRP30), or apM1. Adiponectin circulates in the bloodstream in trimeric, hexameric, and high-molecular-mass species, while different forms of adiponectin …
Predrag Miljic, Dragana Miljic, Joshua William Cain, Márta Korbonits, Vera Popovic
Chronic exposure to high glucocorticoid levels in Cushing’s syndrome (CS) is often associated with alterations in the hemostatic system and the expression of prothrombotic phenotypes. Increased frequency of both atherothrombotic and venous thromboembolic events (VTE) has been reported in patients with CS …
Ioannis D. Kostakis, Kyriaki G. Cholidou, Despina Perrea
The distal nephron, which is the site of the micro-regulation of water absorption and ion handling in the kidneys, is under the control of aldosterone. Impairment of the mineralocorticoid signal transduction pathway results in resistance to the action of aldosterone and of mineralocorticoids in general …
Anthony C. Hackney, Ashley Kallman, Karen P. Hosick, Daniela A. Rubin, Claudio L. Battaglini
OBJECTIVE: To compare the thyroid hormonal responses to high-intensity interval exercise (IE) and steady-state endurance exercise (SEE) in highly trained males (n=15). DESIGN: The IE session consisted of repeated periods of 90-seconds treadmill running at 100-110% …
Neoklis A. Georgopoulos, Anastasia Theodoropoulou, Nikolaos D. Roupas, Loredana Rottstein, Athanasios Tsekouras, Panagiotis Mylonas, George A. Vagenakis, Eftychia Koukkou, Anastasia K. Armeni, George Sakellaropoulos, Michel Leglise, Apostolos G. Vagenakis, Kostas B. Markou
PURPOSE: The aim of this study was to determine the impact of intensive training on adult final height in elite female rhythmic and artistic gymnasts. METHODS: The study included 215 rhythmic gymnasts (RG) and 113 artistic gymnasts (AG) …
Margarita Vlassi, Maria Gazouli, George Paltoglou, Panagiotis Christopoulos, Lina Florentin, Georgia Kassi, George Mastorakos
OBJECTIVE: To investigate the association between Gestational Diabetes Mellitus (GDM) and the variants rs10830963 and rs1387153 in the MTNR1B locus in a sample of the Greek population. DESIGN: One hundred seventy-five unrelated pregnant Greek women …
Ekaterini Koiou, Konstantinos Tziomalos, Ilias Katsikis, Konstantinos Dinas, Elena A. Tsourdi, Eleni A. Kandaraki, Dimitrios Delkos, Efstathios Papadakis, Dimitrios Panidis
OBJECTIVE: We aimed to assess plasma Von Willebrand factor (vWF) levels in women with polycystic ovary syndrome (PCOS) and to compare these levels among the different PCOS phenotypes. DESIGN: We studied 140 women with PCOS and 40 age and body mass index (BMI)- matched healthy women …
Nicos Skordis, Elisavet Efstathiou, Tassos C. Kyriakides, Antria Savvidou, Savvas C. Savva, Leonidas A. Phylactou, Christos Shammas, Vassos Neocleous
OBJECTIVE: The incidence of Type 1 diabetes mellitus (T1DM) in Greek-Cypriot children aged less than 15 years between 1990 and 2009 was examined along with gender differences concerning the age of onset and the seasonal variation at manifestation of the disease …
Fabio Rotondo, Michael Cusimano, Bernd W. Scheithauer, Claire Coire, Eva Horvath, Kalman Kovacs
We report the case of a 49-year-old woman presenting with Cushing disease and visual disturbance. An atypical, aggressive, invasive pituitary tumor regrew despite several surgeries. Detailed morphologic investigation by histology, immunohistochemistry and electron microscopy documented …
Elias E. Mazokopakis, Christos M. Karefilakis, Ioannis K. Starakis
Several conditions and drugs induce subclinical hypothyroidism. We report a case of asymptomatic and reversible subclinical hypothyroidism in a 48-year old woman with minor depressive disorder receiving therapy with escitalopram 20 mg daily for six months …
Anna Maladaki, Maria P. Yavropoulou, Kalliopi Kotsa, Theoni Tranga, Stelios Ventis, John G. Yovos
Gilbert’s syndrome is a common inherited metabolic disorder, caused by genetic aberration in the enzyme UDP-glucuronosyl-transferase 1A1 that leads to reduced glucuronidation of bilirubin. Recent advances in molecular genetics have frequently reported the concurrence of dual genetic …
Konstantinos Laios, Marianna Karamanou, Zenia Saridaki, George Androutsos
The name Aretaeus of Cappadocia has been linked with diabetes more than that of any other physician of antiquity, his texts forming a sophisticated synthesis of the previous knowledge on this disease copiously supplemented by his own observations …
Andres A. Roma
It was with great interest that we read the paper titled Adrenal cortical oncocytoma mimicking pheochromocytoma by Kiriakopoulos A. et al published in the first issue of 2011 of the Journal. A few months later, we were puzzled by a very similar case …