Sodium Iodide Symporter (NIS) and Thyroid

Christine Spitzweg, John C. Morris

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Active transport of iodide into the thyroid gland is a crucial and rate-limiting step in the biosynthesis of thyroid hormones which play an important role in the metabolism, growth and maturation of a variety of organ systems, in particular the nervous system1. Although, iodide transport into the thyroid gland has been known …

Histopathology of Thyroid Tumors. An Overview

Chrisoula D. Scopa

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Thyroid cancer accounts for approximately 1% of total cancer cases in developed countries. It affects all age groups, although it is rare in children. Thyroid tumors are more frequent in women than in men. Despite their relative rarity they exhibit a wide range of morphological patterns and biological behavior which may explain the great interest in these neoplasms of both pathologists and clinicians…

Follicular carcinoma of the thyroid with aggressive metastatic behavior in a pregnant woman: Report of a case and review of the literature

Luciana Parlea, Lisa Fahim, David Munoz, Amir Hanna, Jennifer Anderson, Michael Cusimano, Kalman Kovacs, Geoffrey Gardiner

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Distant metastases as initial presentation of follicular carcinoma of the thyroid is rare, especially in young patients. We report the clinical and pathological features of a 33-year old pregnant patient with follicular carcinoma of the thyroid who presented with widespread bone and lung metastases at the time of diagnosis…

The role of iodine in the evolution of thyroid disease in Greece: from endemic goiter to thyroid autoimmunity

Stelios Fountoulakis, George Philippou, Agathocles Tsatsoulis

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The thyroid gland is dependent on dietary iodine for the production of thyroid hormones, normal iodine requirement being about 150-200μg/day. Long-term deficiency in iodine intake is associated with the development of goiter. When the prevalence of goiter in a population rises above 5-10%, the problem is considered endemic …

Contribution of endocrine parameters in predicting outcome of multiple trauma patients in an intensive care unit

Ioannis Ilias, Konstantinos Stamoulis, Apostolos Armaganidis, Panagiotis Lyberopoulos, Marinella Tzanela, Stylianos Orfanos, Maria Theodorakopoulou, Stylianos Tsagarakis, Ioanna Dimopoulou

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OBJECTIVE: To evaluate whether tentative prognostic models for intensive care unit survival of multiple trauma patients could be improved by including endocrine parameters. DESIGN: Prospective study. Patients: Eighty-three male and 11 female multiple trauma patients…