Maternal vitamin D status in pregnancy: a critical appraisal of current analytical data on maternal and neonatal outcomes

Spyridon N. Karras, Panagiotis Anagnostis, Andrea Petroczi, Cedric Annweiler, Declan P. Naughton, Dimitrios G. Goulis

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Maternal hypovitaminosis D during pregnancy has been associated with a wide spectrum of adverse maternal and neonatal health outcomes, some manifesting stronger associations than others. Research in this field has entered the “era of systematic data evaluation” via the conducting of a series of meta-analyses in an attempt to synthesize …

The interrelationship of serum 1,25-dihydroxyvitamin D, 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D in pregnancy at term: a meta-analysis

Peter D. Papapetrou

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OBJECTIVE: To assess the relationship between circulating 25(OH)D, 1,25(OH)2D, and 24,25(OH)2D in pregnancy at term, and to test the hypothesis that serum 25(OH)D and 24,25(OH)2D are repressed by high serum 1,25(OH)2D levels …

Vitamin D deficiency in white, apparently healthy, free-living adults in a temperate region

Panagiotis N. Singhellakis, Fotini Ch. Malandrinou, Catherine J. Psarrou, Alexandra M. Danelli, Sotirios D. Tsalavoutas, Evangelia S. Constandellou

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OBJECTIVE: The precise incidence of vitamin D deficiency is not known, primarily because there is no consensus on the optimal levels of serum 25(OH)Vitamin D. The aim of the present study was to determine the incidence of vitamin D deficiency in a large group of normal adult volunteers residing in a typical temperate region …

Vitamin D levels in a large Mediterranean cohort: reconsidering normal cut-off values

Marianna Katrinaki, Marilena Kampa, Andrew Margioris, Elias Castanas, Niki Malliaraki

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OBJECTIVE: The determination of the normal range of 25-hydroxyvitamin D [25-(OH)D], though currently based on suppression of PTH levels, still remains a controversial issue. The 25-(OH)D levels exhibit gender and seasonal variability, the latter attributed in part to changes of insolation. DESIGN: The aim of this cross-sectional study was to estimate the levels of 25-(OH)D on the island of Crete …

Low vitamin D status is associated with hypothyroid Hashimoto’s thyroiditis

Dohee Kim

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OBJECTIVE: The association of low vitamin D status with autoimmune thyroid disease (AITD), which includes Hashimoto’s thyroiditis (HT) and Graves’ disease (GD), is controversial. The aim of this study was to investigate the correlation between vitamin D insufficiency and AITD, HT, and GD. DESIGN: Our cross-sectional study included patients …