Endogenous sex steroids and circulating homocysteine in healthy Greek postmenopausal women

George E. Christodoulakos, Irene V. Lambrinoudaki, Demetrios A. Rizos,  Andreas Alexandrou, Apostolos V. Kountouris, George C. Creatsas

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OBJECTIVE: The determinants of serum homocysteine in healthy postmenopausal women remain uncertain. The aim of this study was the assessment of the association of endogenous sex steroids with serum homocysteine levels in healthy postmenopausal women not on hormone therapy…

Bisphenol-A: a new diabetogenic factor?

Paloma Alonso-Magdalena, Ana Belιn Ropero, Sergi Soriano, Ivan Quesada, Angel Nadal

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The aim of this review was to analyze the potential effects of environmental chemicals on homeostatic control related to glycemia and energy balance. Many of the environmental chemicals can mimic or interfere with the action of hormones and are generally referred to as “endocrine disruptors” …

Compensatory adrenal growth in relation to stress of surgery and estradiol in adult male rats

Nicholas Bikas, Joan Gribisi, Joan Messari and Anastasia Sfikakis

ACTH infusion at the time of unilateral adrenalectomy inhibits the early rapid compensatory growth (CAG) in the remaining adrenal. We examined the hypothesis that different duration of surgery and/or the enhanced response to the stress of surgery, induced by estradiol treatment, might modify CAG. Adult male rats untreated …

Sex steroids and sex hormone-binding globulin in postmenopausal women with nonalcoholic fatty liver disease

Stergios A. Polyzos, Jannis Kountouras, Agathocles Tsatsoulis, Efthimia Zafeiriadou, Evangelia Katsiki, Kalliopi Patsiaoura, Christos Zavos, Vasiliki V. Anastasiadou, Aristidis Slavakis

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OBJECTIVE: The evaluation of serum sex steroids and sex hormone-binding globulin (SHBG) levels in postmenopausal women with nonalcoholic fatty liver disease (NAFLD) and their association to the disease severity. DESIGN: Twenty-two postmenopausal women with biopsy-proven NAFLD …

Estradiol and progesterone supplementation during luteal phase improved the receptivity of the endometrium in a patient with a history of diethylstilboestrol exposure in-utero

Dimitris Loutradis, Konstantinos Stefanidis, Erasmia Kiapekou, Evangelia Zapanti, Chrisoula Panitsa-Faflia, Aristidis Antsaklis

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BACKGROUND: Diethylstilboestrol (DES) exposure in-utero has been shown to have negative effects on pregnancy. DES-exposed women are at increased risk of early spontaneous pregnancy loss, ectopic gestation and infertility. DESIGN: A 34-year old woman with a 6-year history of primary infertility is presented. The patient underwent in vitro fertilization (IVF) treatment without success…