Ioannis Ilias, Salvatore Alesci, Philip W. Gold, George P. Chrousos
The longer life expectancy of women than that of men and, therefore, the longer exposure to fracture risk has, at least partially, led to neglect of osteoporosis in men. Recently, unipolar depression, which is 2 times more frequent in women than in men, has been linked to osteoporosis…
Evanthia Diamanti-Kandarakis, Christina Piperi, Georgia Argyrakopoulou, Jiovanna Spina, Lambrini Papanastasiou, Angeliki Bergiele, Dimitrios Panidis
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder characterized by hyperandrogenemia, hyperinsulinemia, insulin resistance, and chronic anovulation. It is the most common endocrine disorder in women of reproductive age with an enigmatic pathophysiologic and molecular basis. The high prevalence of affected …
George E. Christodoulakos, Irene V. Lambrinoudaki, Demetrios A. Rizos, Andreas Alexandrou, Apostolos V. Kountouris, George C. Creatsas
OBJECTIVE: The determinants of serum homocysteine in healthy postmenopausal women remain uncertain. The aim of this study was the assessment of the association of endogenous sex steroids with serum homocysteine levels in healthy postmenopausal women not on hormone therapy…
Theodore K. Alexandrides, Konstantina Kouloubi, Apostolos G. Vagenakis, Spyros Yarmenitis, Trifon Spyridonidis, Pavlos Vassilakos, Dimitris Apostolopoulos
Parathyroid scintigraphy and high-resolution ultrasonography are frequently used as preoperative localization procedures in primary hyperparathyroidism. However, when thyroid disease coexists, their diagnostic accuracy is probably abated. DESIGN: 56 patients with primary hyperparathyroidism were prospectively evaluated with parathyroid scintigraphy…
George N. Zografos, Athina Markou, Chrisanthi Ageli, Nikos Kopanakis, Spiros Koutmos, Gregory Kaltsas, George Piaditis, George I. Papastrati
OBJECTIVE. Laparoscopic adrenalectomy has rapidly replaced open adrenalectomy as the procedure of choice for benign adrenal tumors. The aim of this study was to evaluate the short- and long-term results of 100 consecutive laparoscopic and open adrenalectomies performed during a period of 8.5 years in our Surgical Unit…
Sarantis Livadas, Dimitrios J. Hadjidakis, Maria I. Argyropoulou, Maria Stamatelatou, Dimitrios Kelekis, Sotirios A. Raptis
Acromegaly is caused by excessive growth hormone secretion, usually from a pituitary adenoma. The use of somatostatin analogues as primary or adjunctive therapy has been widely applied in the management of acromegaly. We are aware of only three reported cases of complete shrinkage of a pituitary adenoma after long-term analogue administration…
Ioannis Habeos, Venetsana Kyriazopoulou, Dionysios Chartoumpekis, Agathoklis Psyrogiannis
A 40-year old male residing in the Mediterranean region and afflicted with chronic pancreatitis and diabetes is presented. This is a case of chronic calcific non-alcoholic pancreatitis with characteristic intraductal calculi on abdominal X-ray. Five years following the initial episode of pancreatitis, the patient developed insulin-requiring diabetes mellitus…
Nese Ozbey, Altay Sencer, Sinan Tanyolac, Ramazan Kurt, Serra Sencer, Bilge Bilgic, Inan Turantan, Senay Molvalilar
A patient with an intrasellar germinoma leading to pituitary stalk thickening is reported. The patient, a 24-year old woman, presented with hyperprolactinemia, secondary hypothyroidism, and hypogonadotropic hypogonadism with no evidence of diabetes insipidus. Cerebrospinal fluid (CSF) examination revealed an increased number of lymphocytes and histiocytes…
George Kalantzis, Michael Angelou, Effie Poulakou-Rebelakou
Diabetic retinopathy is a microvascular complication of diabetes mellitus and is a significant cause of new-onset blindness. Diabetic macular changes in the form of yellowish spots and full or partial thickness extravasations through the retina were observed for the first time by Eduard Jäger. In 1855, he published “Beiträge zur Pathologie des Auges” where he included his fundus paintings…