Dragana Miljic, Predrag Miljic, Mirjana Doknic, Sandra Pekic, Marina Djurovic, Milica Colovic, Vera Popovic
BACKGROUND: In rodents, Growth Hormone (GH) has been shown to stimulate coagulation parameters, including Prothrombin Time (PT), activated Partial Thromboplastin Time (aPTT) and vitamin K dependent coagulation factors. However, there are no reports on the influence of GH replacement therapy on global coagulation tests in Growth Hormone Deficiency (GHD)…
Dimitrios G. Goulis, Paschalia K. Iliadou, Athanasios Papanicolaou, Ioannis Georgiou, Anthi Chatzikyriakidou, Spiridon Gerou, Ioannis N. Bontis, Ioannis Papadimas
An 18-year old, phenotypically female individual was examined for primary amenorrhea. Three months before her referral, the patient underwent surgery and a pelvic mass was removed. The physical examination revealed normal female external genitalia, normal breast development, sparse pubic hair and absence of axillary hair…
Maria Papadopoulou, Sofia Doula, Kostas Kitsios, Themistoklis Kaltsas, Konstantina Kosta
The McCune-Albright Syndrome (MAS) is a sporadic rare disease first described in 1936 by McCune and separately by Albright. MAS is characterized by a triad of physical signs: café-au-lait spots, polyostotic fibrous dysplasia and autonomous endocrine hyperfunction. MAS is predominantly observed in girls and is rarely reported in males…
George Androutsos
Since antiquity hermaphrodites have fascinated the mind and excited the imagination. In this paper, such subjects are discussed as legends about the nativity of Hermaphroditus, son of Hermes and Aphrodite, the social status of these bisexual beings, and their fate in Greek-Roman antiquity…
John C. Maroulis, Constantinos Fourtounas, John G. Vlachojannis, Nikolaos Siasos, Dionysios Karavias, Dionysios Chartoumpekis, Ioannis Habeos
A 43-year old Caucasian male with end-stage renal disease presented with painful skin lesions and high calcium phosphate product that did not respond to medical treatment. Skin biopsy confirmed the diagnosis of calciphylaxis. Urgent parathyroidectomy was performed and resulted in decrease in the calcium phosphate product and improvement of his symptoms and signs …
Richard Fleming
Insulin resistance is an important “upstream” driver for reproductive and metabolic abnormalities in women with Polycystic Ovary Syndrome (PCOS). This theoretical background is now supported by substantial evidence for treating women with PCOS with insulin sensitising agents such as metformin or the thiazolidinediones…
Jeffrey R. Garber
Maria Bougoulia, Athanassios Triantos, George Koliakos
OBJECTIVE: To evaluate the levels of Interleukin-6 (IL-6), glutathione peroxidase and isoprostane in obese women and their association with markers of cardiovascular risk factors before and after weight loss. DESIGN: 36 healthy obese women of reproductive age (group A: age (mean ±SD) 35.4 ± 9.2 years, Body Mass Index (BMI) 38.5±7 kg/m2) and 30 healthy, normal weight women …