Amos Pines
A dramatic change has occurred over the past decade with regard to the use of hormones during the postmenopausal period. In the 90’s, the belief in the USA being that there was reason to recommend hormone therapy (HT) for the prevention of coronary artery disease, the guidelines of the American College of Physicians in 1992 were as follows …
Grigorios Kotronoulas, Antonios Stamatakis, Fotini Stylianopoulou
Sleep is an essential ubiquitous biological process, a periodical state of quiescence in which there is minimal processing of sensory information and no interaction with conspecifics or the environment. Despite relevant research on sleep structure and testing of numerous endogenous sleep-affecting chemicals, questions as to the precise mechanisms …
Leonidas H. Duntas, Christos Doumas
Several studies have revealed an increased incidence of thyroid cancer in volcanic areas around the world. Hawaii and the Philippines on the rim of the Pacific Ocean, where the greatest number of volcanoes are located at convergent plate boundaries, are among the regions with the highest incidence of thyroid carcinoma worldwide. Iceland is another region also rich in volcanoes …
Spyros Karras, Themistoklis Tzotzas, Gerasimos E. Krassas
Antithyroid drugs (ATD) are widely used by endocrinologists all over the world for the treatment of Graves’ disease (GD) in the general population and in lactating thyrotoxic mothers.1,2 Traditionally, these agents produce minor side effects (rash, fever, urticaria) in 5-10% of the treated patients …
Menelaos L. Batrinos
It is now well established that hyperprolactinaemia is not rare and in the majority of cases is caused by a pituitary tumor, a prolactinoma. However, despite a plethora of relevant publications there are still certain questions that have not been adequately addressed: 1. What is the upper normal level of serum prolactin beyond which the condition should be characterized as hyperprolactinaemia …
Nectaria Xita, Leandros Lazaros, Ioannis Georgiou, Agathocles Tsatsoulis
OBJECTIVE: Insulin resistance is a key factor in the pathogenesis of polycystic ovary syndrome (PCOS). Peroxisome proliferator-activated-receptor-γ (PPAR-γ) has been implicated in insulin resistance and adiposity. The aim of the study was to investigate the possible involvement of the Pro12Ala polymorphism …
Andrew Collier, Sujoy Ghosh, Mario Hair, Iqbal Malik, Jim McGarvie
OBJECTIVE: Radioiodine therapy is the most commonly used therapy for patients with Graves’ disease (GD) in the United Kingdom. It is considered safe, effective and relatively inexpensive. The aim of our study was to examine the outcome of 131Iodine therapy in patients with GD when two different activities of 131Iodine were used …
Mahin Hashemipour, Roya Kelishadi, Javad Shapouri, Nizal Sarrafzadegan, Masoud Amini, Naser Tavakoli, Ahmad Movahedian-Attar, Parisa Mirmoghtadaee, Parinaz Poursafa
OBJECTIVE: Zinc, an essential trace element and a component of many enzymes, is involved in the synthesis, storage and release of insulin. The aim of the present study was to assess the effect of zinc supplementation on insulin resistance and components of the metabolic syndrome in prepubertal obese children. DESIGN: This triple-masked …
Sena Yesil, Baris Akinci, Serkan Yener, Firat Bayraktar, Ozalp Karabay, Hasan Havitcioglu, Nur Yapar, Atay Atabey5 Yasin Kucukyavas, Abdurrahman Comlekci, Sevinc Eraslan
OBJECTIVE: Prediction of diabetic foot ulcer outcome may be helpful for clinicians in optimizing and individualizing management strategy. The aim of the present study was to examine the possibility of predicting the outcome of patients with diabetic foot ulcers by using easily assessed clinical and laboratory parameters at baseline …
John Doupis, Charalambos Stavrianos, Katerina Saltiki, Emily Mantzou, Antonios Mastrokostopoulos, George Philippou, Maria Alevizaki
Albania is an in-transition country in the Balkan area and among those with the lowest per capita income in Europe. The Health System of Albania, as the Albanian society itself, is now taking its first steps in adopting the Western financial model. Globalization in modern Western society, even at the level of dietary practices …
Luis V. Syro, Bernd W. Scheithauer, Leon D. Ortiz, Camilo E. Fadul, Eva Horvath, Fabio Rotondo, Kalman Kovacs
The patient was a 70-year-old man with a recurrent pituitary tumor. Three surgeries were performed but the tumor recurred. Based on histologic, immunohistochemical and ultrastructural studies, the diagnosis of oncocytic gonadotrophic pituitary adenoma was made. The tumor was a macroadenoma partly immunopositive for LH …