Panagiotis Nomikos, Rudolf Fahlbusch, Michael Buchfelder
Despite recent and ongoing advances in the pharmacological and radiotherapeutic management of pituitary tumors, surgery remains the therapy of choice for the vast majority of these lesions. Both transsphenoidal and transcranial microsurgery of pituitary adenomas and of other sella lesions are well established, safe and highly efficient therapeutic procedures…
Eustratios V. Gotzaridis, Athina Markou, Zdenek Gregor
Patients with type 1 diabetes mellitus experience a high incidence of severe ocular complications and are more likely to have significant ocular problems during their lifetimes. Patients with type 2 diabetes mellitus (DM2), however, make up the majority of clinical cases with diabetic eye disease because of the higher incidence of DM2…
Chrisoula D. Scopa
Thyroid cancer accounts for approximately 1% of total cancer cases in developed countries. It affects all age groups, although it is rare in children. Thyroid tumors are more frequent in women than in men. Despite their relative rarity they exhibit a wide range of morphological patterns and biological behavior which may explain the great interest in these neoplasms of both pathologists and clinicians…
Themistoklis Tzotzas, Theodoros Konstantinidis, Maria Bougoulia, Gerasimos E. Krassas
The aim of this large scale epidemiological cross-sectional study was to investigate potential factors, such as age, gender, socioeconomic status (measured as educational level and profession), smoking habits and physical activity, that could influence Body Mass Index (BMI) in a large sample of Greeks of Central Macedonia. Overall, 4032 adults (1296 males and 2736 females), age: 44.3±14.5 y (mean ± SD) participated in this study.
A. Mortoglou, H. Candiloros
In order to examine the significance of differences in the triiodothyronine/thyroxine (T3/T4) ratio in the achievement of euthyroidism and in different thyroidal diseases, we studied 1050 subjects: 233 were euthyroid (Eu), 239 hypothyroid (Hypo) with initial TSH levels >15 mU/L, 273 hypothyroid on substitution therapy with L-thyroxine alone and TSH values of 0.35-3.5 mU/L, (hypoRx), 236 hyperthyroid (hyper) and 69 …
Justin K. Lawrence, Eamonn R. Maher, Richard Sheaves, Ashley B. Grossman
Phaeochromocytomas (PC) and paragangliomas are disorders of the sympatho-adrenomedullary system. They are chromaffin-containing neuroendocrine tumors of neural crest origin that contain catecholamine-secreting granules: they arise from either the adrenal medulla (phaeochromocytomas) or from extra-adrenal neural crest derivatives e.g. the sympathetic chain (paragangliomas)…
Dimitra Zianni, Marinella Tzanela, Serafim Klimopoulos, N.C. Thalassinos
A 61-year old female presented with paroxysmal hypertension and a 4.5cm left adrenal mass on CT scan. Repeated measurements of 24-hour urinary fractionated metanephrines, total catecholamines and vanillylmandelic acid (VMA) were within normal range. A further scintigraphic study …