Comparison of color-Doppler and qualitative and quantitative strain-elastography for differentiation of thyroid nodules in daily practice

Manuela Götzberger, Susanne Krueger, Roland Gärtner, Martin Reincke, Matthias Pichler, Gerald Assmann, Thomas Mussack, Michael Zimmermann, Veit Gülberg

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OBJECTIVE: Strain-elastography provides a new ultrasound-based method that can offer information about the stiffness of thyroid nodules as an indicator of malignancy. The aim of our study was to compare the utility of color-Doppler and strain-elastography in differentiating between benign and malignant nodules. DESIGN AND METHODS: 77 thyroid nodules (70 benign and 7 malignant) from 70 unselected patients (48 female/22 male, mean age 49.7±14.3 years) were evaluated with color-Doppler …

Contribution of high-resolution ultrasonography in the differential diagnosis of benign from malignant thyroid nodules

Emmanuel Varverakis, Evaggelos Neonakis

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The purpose of this study was to investigate the value of “high-resolution ultrasonography” in the differential diagnosis of benign from malignant thyroid nodules. The study included ultrasonography examination of 77 patients with thyroid nodules, who underwent thyroidectomy. The histological findings were subsequently compared …

Influence of cigarette smoking on thyroid function, goiter formation and autoimmune thyroid disorders

Nikolaos Pontikides, Gerassimos E. Krassas

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Both smoking and thyroid dysfunction are frequent in the general population. Many studies have shown that cigarette smoking interferes with thyroid function and with the evolution of thyroid pathology (e.g. goiter formation and thyroid cancer development). Some studies have also suggested a significant correlation of Graves’ hyperthyroidism and Graves’ ophthalmopathy…

Differentiated thyroid cancer in Greece: 1963-2000. Relation to demographic and environmental factors

Ioannis Ilias, Maria Alevizaki, Elli Lakka-Papadodima, Demetrios A. Koutras

Thyroid cancer (TC) is a relatively rare neoplasia, accounting for 0.35%-0.38% of total deaths due to cancer in Greece. Environmental/nutritional factors are considered to play a role in its pathogenesis. The aim of this retrospective review of patients’ histories from three of the largest specialized centers in southern Greece, from 1963 to 2000…

Unresolved issues, dilemmas and points of interest in thyroid cancer: A current perspective

Nicholas J Sarlis, Loukas Gourgiotis

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Thyroid cancer (TC) is the commonest endocrine malignancy. In the overwhelming majority of cases, thyroid carcinomas are well-differentiated malignancies that respond favorably to treatment; however, this outcome cannot be absolutely guaranteed. The absence of large prospective randomized clinical trials in TC—due to its low incidence and protracted clinical course in cases with persistent/recurrent metastatic disease—results in considerable debates regarding the optimal treatment and follow-up regimens in this malignancy…