Katerina Saltiki, Maria Alevizaki
Coronary heart disease is the main cause of death in women. Women during reproductive years are at lower risk for coronary heart disease than men but this difference tends to disappear after the menopause. In this article, we briefly review the clinical and experimental data which highlight the protective role of endogenous estrogens in the pathogenesis of coronary heart disease …
Adeeb Shehzad, Waqas Iqbal, Omer Shehzad, Young Sup Lee
Adiponectin is a white and brown adipose tissue hormone, also known as gelatin-binding protein-28 (GBP28), AdipoQ, adipocyte complement-related protein (ACRP30), or apM1. Adiponectin circulates in the bloodstream in trimeric, hexameric, and high-molecular-mass species, while different forms of adiponectin …
Georgios Efstratiadis, Konstantinos Koskinas, Efstathios Pagourelias
Cardiovascular mortality is significantly increased among patients with end-stage renal disease. The commonly observed vascular calcification in such patients has been considered as one of the causative factors. In patients undergoing dialysis, the incidence of coronary artery calcification is 2-5 times higher compared to patients with normal renal function and angiographically demonstrated coronary artery disease…
Lampros Fotis, Dionysios Giannakopoulos, Lela Stamogiannou, Maria Xatzipsalti
In 1995 David Barker formulated the ‘Barker hypothesis’ according to which there is a correlation between undernutrition in utero and several diseases in adult life. More specifically, undernutrition in utero permanently affects the vascular bed, resulting in a predisposition to diseases later on …
Melpomeni Peppa, Helen Vlassara
Diabetes mellitus, especially type 2 diabetes, is increasing at an alarming rate and is considered as one of the main threats to human health in the 21st century, in both developed and developing nations.1
More than 150 million people currently have diabetes, and twice that number is at high risk of developing diabetes in the next 5-10 years …
Ilpo Huhtaniemi, Juuso I. Mäkinen, Antti Perheentupa, Olli T. Raitakari
Interest has arisen during the last 10 years as to the possible connection between the age-related decline in androgen production and symptoms of ageing in men. A new ageing-related syndrome with several descriptive names …
Katerina Saltiki, Adrianna Cimponeriu, Kyriaki Lili, Melpomeni Peppa, Eleni Anastasiou, Maria Alevizaki
Objective: Coronary artery disease (CAD) risk increases in women after the menopause. The aim of this study was to determine the effect of diabetes on the severity of CAD in postmenopausal women undergoing coronary angiography. Design: 180 postmenopausal women underwent coronary angiography for suspected CAD …
Gulcin Akinci, Baris Akinci, Senol Coskun, Petek Bayindir, Zeliha Hekimsoy, Bilgin Ozmen
Objective: Childhood obesity is associated with impaired endothelial function, insulin resistance and inflammation. Being at risk for overweight has been defined as having a body mass index (BMI) between the 85th and 94th percentile for age and sex. In this study, we looked for features linked to cardiovascular risk in children who are at risk for overweight …