Tag: insulin resistance
Early microvascular and macrovascular dysfunction is not accompanied by structural arterial injury in polycystic ovary syndrome
Krystallenia Alexandraki, Athanasios D. Protogerou, Theodoros G. Papaioannou, Christina Piperi, George Mastorakos, John Lekakis, Dimitrios Panidis, Evanthia Diamanti-Kandarakis
OBJECTIVE: During the last decade cardiovascular risk factors and endothelial dysfunction have been shown to be present early in life in women with Polycystic Ovary Syndrome (PCOS). The aim of the present study was a global assessment of abnormalities in the arterial bed of young women with PCOS by non-invasive, reproducible methods…
Improvement of insulin sensitivity in patients with type 2 diabetes mellitus after oral administration of alpha-lipoic acid
Petya Kamenova
BACKGROUND: Amelioration of insulin resistance could improve both glycaemic control and cardiovascular risk factors in patients with type 2 diabetes mellitus. Alpha-lipoic acid has been shown to improve insulin action after parenteral administration. OBJECTIVE: the aim of the study was to assess the effect of oral administration of alpha-lipoic acid on insulin sensitivity in patients with type 2 diabetes…
Ghrelin and leptin levels in obese adolescents. Relationship with body fat and insulin resistance
Charilaos Stylianou, Assimina Galli-Tsinopoulou, Dimitrios Farmakiotis, Israel Rousso, Michael Karamouzis, George Koliakos, Sanda Nousia-Arvanitakis
OBJECTIVE: Ghrelin and leptin levels are influenced by body fat (BF%), pubertal stage and possibly insulin resistance (IR). The aim of our study was: 1) To compare fasting ghrelin and leptin levels between obese and non-obese, adolescents, 2) to investigate possible correlations of these hormones with BF %, as well as IR…