Athanasios Diamandopoulos, Pavlos Goudas, Demetra Patsy St. Andrew's Regional Hospital, Nephrology Unit, Patras, 263 35, Greece Physicians and scholars of antiquity were well aware that the function of the testicles of humans and animals was not restricted to the production of sperm alone but that it was directly related to sexuality and secondary sexual characteristics. Read More
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Recent developments in transsphenoidal surgery of pituitary tumors
Panagiotis Nomikos1, Rudolf Fahlbusch2, Michael Buchfelder1 1Department of Neurosurgery, University of Goettingen, Goettingen, Germany and 2Department of Neurosurgery, University of Erlangen-Nuremberg, Erlangen, Germany INTRODUCTION Despite recent and ongoing advances in the pharmacological and radiotherapeutic management of pituitary tumors, surgery remains the therapy of choice for the vast majority of these lesions. Both transsphenoidal and transcranial Read More
Adrenal Incidentaloma (Adrenaloma)
Dimitrios A. Linos First Surgical Clinic Hygeia Hospital, Athens, Greece and Massachusetts General Hospital, Boston, MA USA Abstract The management of adrenalomas should include the following:1. A detailed history and physical examination to detect subtle evidence of hormonal hypersecretion or the possibility of metastatic carcinoma.2. Hormonal studies: • Short dexamethasone suppression test (2 mg of Read More
Adrenal Incidentalomas or Adrenalomas: The NIH state-of-the-science conference statement
In this issue of Hormones, Dr. Dimitrios Linos has written a comprehensive review on adrenal incidentalomas, for which he proposes the more economical term "adrenalomas"1,2. The management of these incidentally discovered, common masses has many controversies stemming from the fact that a minute proportion of them can be malignant2. There are two known common conditions Read More
Primary Adrenal lymphoma presented with adrenal insufficiency
Evanthia Diamanti-Kandarakis1, Pantelis Chatzismalis1, Frangiskos Economou1, Stefanos Lazarides1, Athena Androulaki2, Grigorios Kouraklis3 1Endocrine Section, First Department of Medicine, Athens University Medical School, 2Department of Pathology, Laiko General Hospital, 32nd Department of Surgery Athens University Medical School, Athens, Greece Abstract We report a 71-year old man who presented with symptoms of adrenal insufficiency and large bilateral Read More
Treatment of recurrent gastrointestinal haemorrhage in a patient with von Willebrand\’s disease with administration of octreotide LAR and propranolol
Napoleon Krikis, Konstantinos Tziomalos, Vasilios Perifanis, Sofia Vakalopoulou, Asterios Karagiannis, Vasilia Garypidou, Fedon Harsoulis Second Propedeutic Department of Internal Medicine, Aristotelian University of Thessaloniki, Ippokration General Hospital, Thessaloniki, Greece Abstract We report a patient with von Willebrand' s disease who had had recurrent and life-threatening bleeding from the gastrointestinal tract. Despite extensive investigation, no apparent Read More
Langerhans\’ cell histiocytosis in an adult patient manifested as recurrent skull lesions and Diabetes Insipidus
Polyzois Makras1, Dimitris Papadogias1, Chrysoula Samara2, Athanasios Zetos3, Gregory Kaltsas1, George Piaditis1, Antony C Chu 4 1Department of Endocrinology, 2Radiology, G. Genimatas General Hospital, Athens Greece; 39th Pulmonary Department, "SOTIRIA" Hospital, Athens, Greece; 4Unit of Dermatology, Royal Postgraduate Medical School, London, UK Abstract We describe a 57-year old female with the diagnosis of skull and Read More
Clinical aspects of hyperthyroidism in hospitalised patients in Albania
Feçor Agaçi Endocrinology and Diabetes Service, University Hospital Center "Mother Teresa", Tirana, Albania Abstract The purpose of this study was to evaluate certain clinical aspects of hyperthyroidism in Albania, which is an iodine deficient country, as it is known that iodine intake may influence the type of thyroid hyperfunction. The files of sixty-six patients with Read More
Increased leptin levels in preeclampsia: associations with BMI, estrogen and SHBG levels
Acromite Michael, Ziotopoulou Mary, Orlova Christine, Mantzoros Christos Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA USA Abstract Leptin is secreted mainly by the white adipose tissue but is also synthesized in several non-adipose tissue organs including the placenta. Serum leptin levels are increased in normal pregnancies and are higher Read More
Pegvisomant: a new treatment modality for acromegaly
Niki Karavitaki, John AH Wass Department of Endocrinology, the Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK Abstract Acromegaly, a multisystemic disease resulting from excessive growth hormone (GH) and insulin-like growth factor-I (IGF-I) levels in adults, is associated with a two-to-threefold increase in mortality. The available treatment options (surgery, radiotherapy and medical Read More