Panayota Mitrou, Sotirios A. Raptis, George Dimitriadis
The aim of this review is to summarize the mechanisms underlying insulin resistance in morbid obesity. Glucose regulation by insulin depends on the suppression of endogenous glucose production and stimulation of glucose disposal. In morbid obesity, glucose production by the liver is increased …
Christos Tsatsanis, Eirini Dermitzaki, Pavlina Avgoustinaki, Niki Malliaraki, Vasilis Mytaras, Andrew N. Margioris
Adipose tissue produces factors, including adipokines, cytokines and chemokines which, when released, systemically exert endocrine effects on multiple tissues thereby affecting their physiology. Adipokines also affect the hypothalamic-pituitary-gonadal (HPG) axis both centrally, at the hypothalamic-pituitary level …
Nikolaos D. Roupas, Irene Mamali, Spyros Maragkos, Lydia Leonidou, Anastasia K. Armeni, George K. Markantes, Athanasios Tsekouras, George C. Sakellaropoulos, Kostas B. Markou, Neoklis A. Georgopoulos
OBJECTIVE: To evaluate the effect of prolonged intensive aerobic exercise and acute energy deficit (180 km ultra-marathon race) on serum leptin, adiponectin, resistin and visfatin levels and their association and interaction with serum cortisol and insulin levels in highly trained ultra-endurance runners …
Sadashiv, Sunita Tiwari, Bhola Nath Paul, Sandeep Kumar, Abhijit Chandra, S. Dhananjai, Mahendra Pal Singh Negi
OBJECTIVE: The present study evaluates adiponectin mRNA in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) and also evaluates its association with metabolic risk factors in postmenopausal obese women. DESIGN: A case control study was carried out on postmenopausal women …