Insulin resistance and risk of renal cell cancer: a case-control study

Themistoklis N. Spyridopoulos, Nick Dessypris, Antonis G. Antoniadis, Spyros Gialamas, Constantine N. Antonopoulos, Konstantina Katsifoti, Hans-Olov Adami, George P. Chrousos, Eleni Th. Petridou, and the Obesity and Cancer Oncology Group

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OBJECTIVE: Obesity and diabetes are considered risk factors for Renal Cell Carcinoma (RCC). We aimed to explore whether insulin resistance (IR) plays an independent role in the development of RCC. DESIGN: In a hospital-based case-control study, we analyzed serum glucose …

The AGT and the GNB3 polymorphisms and insulin resistance in prehypertension

Christos Maniotis, Klio Chantziara, Panagiotis Kokkoris, Dimitrios Papadogiannis, Constantinos Andreou, Constantinos Tsioufis, Georgios Vaiopoulos, Christodoulos Stefanadis

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OBJECTIVE: This study surveyed the frequencies of single nucleotide polymorphisms (SNPs) M235T AGT and C825T GNB3, and their association with insulin resistance, other biochemical markers and qualitative variables in subjects with high normal blood pressure and/or prehypertension in the Greek population …

Evaluation of markers of inflammation, insulin resistance and endothelial dysfunction in children at risk for overweight

Gulcin Akinci, Baris Akinci, Senol Coskun, Petek Bayindir, Zeliha Hekimsoy, Bilgin Ozmen

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Objective: Childhood obesity is associated with impaired endothelial function, insulin resistance and inflammation. Being at risk for overweight has been defined as having a body mass index (BMI) between the 85th and 94th percentile for age and sex. In this study, we looked for features linked to cardiovascular risk in children who are at risk for overweight …