Thyroid nodules – Stepwise diagnosis and management

Stergios A. Polyzos, Marina Kita, Avraam Avramidis

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Thyroid nodules are common in clinical practice. They may be solitary within a “normal” thyroid gland or dominant within a multinodular goiter. The incidence of thyroid nodules has been on the rise in recent decades, mainly due to the wider use of neck imaging. Therefore, the incidental finding of a thyroid nodule in an asymptomatic patient is not rare…

The role of iodine in the evolution of thyroid disease in Greece: from endemic goiter to thyroid autoimmunity

Stelios Fountoulakis, George Philippou, Agathocles Tsatsoulis

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The thyroid gland is dependent on dietary iodine for the production of thyroid hormones, normal iodine requirement being about 150-200μg/day. Long-term deficiency in iodine intake is associated with the development of goiter. When the prevalence of goiter in a population rises above 5-10%, the problem is considered endemic …

Influence of cigarette smoking on thyroid function, goiter formation and autoimmune thyroid disorders

Nikolaos Pontikides, Gerassimos E. Krassas

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Both smoking and thyroid dysfunction are frequent in the general population. Many studies have shown that cigarette smoking interferes with thyroid function and with the evolution of thyroid pathology (e.g. goiter formation and thyroid cancer development). Some studies have also suggested a significant correlation of Graves’ hyperthyroidism and Graves’ ophthalmopathy…

Epidemiological characteristics of children with autoimmune thyroid disease

Vasiliki Skarpa, Eleni Κousta, Athanasia Tertipi, Konstantinos Anyfandakis, Marina Vakaki, Maria Dolianiti, Aspasia Fotinou, Asteroula Papathanasiou

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OBSECTIVE: Chronic autoimmune thyroiditis (AT) is the most common cause of thyroid disease in children. The aim of the study was to define the epidemiological clinical and laboratory characteristics of children and adolescents with AT. DESIGN: Various parameters including thyroid ultrasonography of 228 children and adolescents …

Increased goiter prevalence in schoolchildren of Isfahan despite long-term iodine sufficiency

Mansour Siavash, Ammar Hassanzadeh Keshteli, Mahin Hashemipour, Masoud Amini

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OBJECTIVE: Iodine Deficiency (ID) was for years considered a contributing factor for endemic goiter in Iran. The present study was conducted to assess the goiter prevalence and iodine status in schoolchildren of Isfahan 16 years after the initiation of salt iodization in Iran …

Diabetes mellitus in a girl with thyroid hormone resistance syndrome: a little recognized interaction between the two diseases

Stefano Stagi, Cristina Manoni, Valentina Cirello, Danila Covelli, Sabrina Giglio, Francesco Chiarelli, Salvatore Seminara, Maurizio de Martino

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The syndrome of resistance to thyroid hormone (RTH) is characterized by elevated serum free thyroid hormones (FT4 and FT3) in the presence of unsuppressed TSH levels, reflecting resistance to the normal negative feedback mechanisms in the hypothalamus and pituitary …

The Republic of Srpska Iodine Deficiency Survey 2006

Amela Lolic, Νenad Prodanovic

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Objective: A survey related to iodine deficiency in the Republic of Srpska was first conducted in 1999 and resulted in the adoption of regulations concerning the quality of salt for human consumption. In order to reassess iodine status, we conducted the Republic of Srpska Iodine Deficiency Survey in 2006 …