Association of genetic variants of vit D binding protein (DBP/GC) and of the enzyme catalyzing its 25-hydroxylation (DCYP2R1) and serum vit D in postmenopausal women

Wen Xu, Jing Sun, Wenbo Wang, Xiran Wang, Yan Jiang, Wei Huang, Xin Zheng, Qiuping Wang, Zhiwei Ning, Yu Pei, Min Nie, Mei Li, Ou Wang, Xiaoping Xing, Wei Yu, Qiang Lin, Ling Xu, Weibo Xia

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OBJECTIVE: To determine if GC (group-specific component globulin) and CYP2R1 genetic variants have an association with serum 25-OHD3 levels, BMD or bone turnover markers in a population of Chinese postmenopausal women …

The combined effect of MC4R and FTO risk alleles on childhood obesity in Greece

Natalia Lazopoulou, Eleana Gkioka, Ioanna Ntalla, Panagiota Pervanidou, Alexandra-Maria Magiakou, Eleftheria Roma-Giannikou, George P. Chrousos, Ioannis Papassotiriou, George Dedoussis, Christina Kanaka-Gantenbein

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OBJECTIVE: Single nucleotide polymorphism (SNP) risk alleles of obesogenic genes, such as the fat mass and obesity-associated protein (FTO) and the melanocortin-4 receptor (MC4R) gene, have been described in both paediatrics and adult populations …