Constantine A. Stratakis
In the mid 1980’s, two advances revolutionized Medicine in a way that is comparable only to some of the most important events in the approximately 3,000 years of its history. The first was the introduction of the concept of “positional cloning”, i.e. the idea that one can identify genes for human disease though knowing nothing or very little about their function…
Elias E. Mazokopakis, Anastasios A. Tzortzinis, Elpida I. Dalieraki-Ott, Athanasios N. Tsartsalis, Periklis K. Syros, Christos M. Karefilakis, Maria G. Papadomanolaki, Ioannis K. Starakis
OBJECTIVE: The association between Hashimoto’s thyroiditis (HT) and papillary thyroid carcinoma (PTC) remains controversial in medical bibliography. The main objective of our study was to determine the prevalence of PTC and HT coexistence in histopathologic material of thyroidectomized patients. DESIGN: In a retrospective study …
Vassiliki Pelekanou, George Notas, Efstathios N. Stathopoulos, Elias Castanas, Marilena Kampa
Prostate cancer is one of the most common malignancies and causes of death among men in western societies. It has thus attracted the interest of the scientific community, which has resulted in great improvements in survival rates in recent years. As early as the 1940s, Huggins and Hodges first demonstrated that prostate cancer is androgen dependent …
Konstantinos A. Paschos, Efterpi Chouridou, Maria Koureta, Maria Lambropoulou, George Kolios, Ekaterini Chatzaki
The corticotropin-releasing factor (CRF) system plays a crucial regulatory role in the adaptation to exogenous and endogenous stress stimuli, as well as homeostasis. Apart from the central nervous system (CNS), the members of this neuropeptide family extend their actions in the periphery …
Marilena Kampa, Vassiliki Pelekanou, George Notas, Efstathios N. Stathopoulos, Elias Castanas
Ioannis Vakalopoulos, Petros Dimou, Ioannis Anagnostou, Theodosia Zeginiadou
While cancer, and especially testicular cancer and Hodgkin’s disease, affects male fertility in many ways, the current increase of survival of male cancer patients of reproductive age or earlier has emerged as a new challenge to their subsequent ability to father children. Cancer treatments, including surgery, radiotherapy and chemotherapy …
Katherine E. Akester, Noel Somasundaram, Salvador Diaz-Cano, Ashley B. Grossman
Most clinicians assume that a thyroid mass which appears to be malignant is most likely a tumour arising from thyroid cells. We present a case where the thyroid malignancy was associated with a degree of systemic clinical and biochemical disturbance which suggested alternative diagnoses, and in which fine-needle aspiration revealed that the patient had a thyroid lymphoma …