Cushing’s syndrome in pregnancy: Report of a case and review of the literature

Marina Kita, Maria Sakalidou, Athanasios Saratzis, Sarris Ioannis, Avraam Avramides

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Cushing’s syndrome (CS) during pregnancy is a rare nosology with only a few cases reported in the literature. Misdiagnosis is common, as the syndrome may be easily confused with preeclampsia or gestational diabetes. CS during pregnancy is usually associated with severe maternal and fetal complications..

A unique case of a benign adrenocortical tumor with triple secretion of cortisol, androgens, and aldosterone. Development of multiple sclerosis after surgical removal of the tumor

Athina Markou, Kaity Tsigou, Dimitrios Papadogias, Kostas Kossyvakis, Kyriakos Vamvakidis, Theodora Kounadi, George Piaditis

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We present a 39-year old female with a benign adrenal tumor characterized by autonomous secretion of cortisol, androgens, and aldosterone. The patient presented with a 4-year history of hypertension and severe hirsutism. Baseline investigations revealed elevated testosterone, androstendione, and 17OH progesterone with normal levels of dehydroepiandrosterone sulfate…

The diagnosis and differential diagnosis of endogenous Cushing’s syndrome

Polyzois Makras, Georgios Toloumis, Dimitrios Papadogias, Gregory A. Kaltsas, Michael Besser

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Cushing’s syndrome (CS) is a physically and psychologically disabling disease associated with high morbidity resulting from inappropriate elevation of circulating free cortisol levels. The main features of CS are disturbance of the normal circadian rhythm of cortisol secretion, impairment of the normal feedback of the hypothalamo-pituitary-adrenal (HPA)-axis …