Disappearance of a growth hormone secreting macro adenoma during long-term somatostatin analogue administration and recurrence following somatostatin withdrawal

Sarantis Livadas,1 Dimitrios J. Hadjidakis,1 Maria I. Argyropoulou,2 Maria Stamatelatou,1 Dimitrios Kelekis,3 Sotirios A. Raptis1 1Second Department of Internal Medicine-Propaedeutic, Research Institute and Diabetes Centre, Athens University Medical School, “Attikon” University Hospital, Athens, 2Department of Radiology, Ioannina University Medical School, Ioannina, 32nd Department of Radiology, Athens University Medical School, “Attikon” University Hospital, Athens, Greece Abstract Read More

Fibrocalculous pancreatic diabetes in a patient residing

Ioannis Habeos, Venetsana Kyriazopoulou, Dionysios Chartoumpekis, Agathoklis Psyrogiannis Division of Endocrinology and Diabetes, Department of Internal Medicine, Patras University Medical School, Patras, Greece Abstract A 40-year old male residing in the Mediterranean region and afflicted with chronic pancreatitis and diabetes is presented. This is a case of chronic calcific non-alcoholic pancreatitis with characteristic intraductal calculi Read More

An intrasellar germinoma with normal cerebrospinal fluid ?-HCG concentrations misdiagnosed as hypophysitis

Nese Ozbey,1 Altay Sencer,2 Sinan Tanyolac,1 Ramazan Kurt,1 Serra Sencer,3 Bilge Bilgic,4 Inan Turantan,2 Senay Molvalilar1 1Department of Internal Medicine, Division of Endocrinology, 2Department of Neurosurgery, 3Department of Radiology, 4Department of Pathology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey Abstract A patient with an intrasellar germinoma leading to pituitary stalk thickening is reported. The patient, Read More

Diabetic retinopathy: An historical assessment

George Kalantzis, Michael Angelou, Effie Poulakou-Rebelakou Department of History of Medicine, Athens University Medical School, Athens, Greece Abstract Diabetic retinopathy is a microvascular complication of diabetes mellitus and is a significant cause of new-onset blindness. Diabetic macular changes in the form of yellowish spots and full or partial thickness extravasations through the retina were observed Read More

Hormones in sports: growth hormone abuse

Evanthia Diamanti-Kandarakis, Dimitrios Tsilakis, Stefanos Lazarides, Helen Kandarakis, Angeliki Bergele Endocrine Section, First Department of Medicine, Medical School, University of Athens, Athens, Greece General considerations "Altius, citius, fortius": higher, faster, stronger. These words from ancient times still today express the endeavour of athletes to beat records and gain victory. This endeavour has never been easy Read More

The human skin as a hormone target and an endocrine gland

Christos C. Zouboulis Department of Dermatology, Charité University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany Abstract Hormones influence the development and function of human skin which also produces and releases hormones. Recently attention has been focused on identifying and understanding the complex endocrine properties of human skin, such as expression and function of specific hormone Read More

Estrogens and brain function

Athina Markou1, Theodora Duka2, Gordana M. Prelevic3 1Department of Endocrinology and Diabetes, G. Gennimatas Hospital, Athens, Greece, 2Department of Experimental Psychology, School of Biological Sciences, Sussex University, Falmer, UK, 3Department of Endocrinology, Royal Free and University College School of Medicine, London, UK Abstract Cognitive decline is well recognized during ageing but is often accelerated in Read More

Weightlessness and skeleton homeostasis

Konstantinos Ziambaras1, Roberto Civitelli2, Stathis S. Papavasiliou1 1Department of Endocrinology, University of Crete Medical School, Iraklion, Grete, Greece, 2Division of Bone and Mineral Diseases, Washington University School of Medicine, St Louis MO, USA Abstract As human beings venture into space in the 21st century, they will be confronted with a "hypodynamic" and thus hostile environment Read More

Advanced glycation end products and diabetic complications: A General overview

Melpomeni Peppa, Helen Vlassara Division of Experimental Diabetes and Aging, Department of Geriatrics, Mount Sinai School of Medicine, NY, NY 10029, USA Abstract Diabetes mellitus, especially type 2 diabetes is increasing at an alarming rate reaching epidemic proportions. Although hyperglycemia has been considered as playing an important role in the pathogenesis of diabetic complications, the Read More

Applications of genomic medicine in endocrinology and post-genomic endocrine research

Constantine A. Stratakis Heritable Disorders Branch, and the Section on Endocrinology & Genetics, Developmental Endocrinology Branch, (DEB), National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD 20892, USA Abstract In the mid 1980's, two advances revolutionized Medicine in a way that is comparable only to some of the Read More