A short evolutionary history of FSH-stimulated spermatogenesis

Ilpo Huhtaniemi

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It is well established in various experimental models that luteinizing hormone (LH) stimulated testosterone (T) production of Leydig cells is the key endocrine stimulus of spermatogenesis. The role of the other gonadotrophin, follicle-stimulating hormone (FSH), is as yet somewhat unclear given that several clinical conditions …

Magnetization transfer imaging of the pituitary gland

Maria I. Argyropoulou, Dimitrios Nikiforos Kiortsis

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Magnetization transfer (MT) techniques provide tissue contrast which depends mainly on the concentration of macromolecules. The magnetization transfer phenomenon is determined by the restricted macromolecular protons and is quantified by the magnetization transfer ratio (MTR). Since many macromolecular structures are implicated in the secretory activity of the pituitary gland …

Pituitary disorders in pregnancy

Alexandra Chrisoulidou, Maria Boudina, Niki Karavitaki, Eleni Bili, John Wass

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The pituitary gland is significantly affected during gestation in terms of both size and function. Due to this physiologic adaptation, endocrine evaluation and interpretation of imaging is far more complex than in the non-pregnant state. Pituitary disorders are rare in pregnancy, as they are usually associated with gonadal dysfunction …

Hypophysis. From outgrowth, to ocular disorder to pituitary gland

Konstantinos Laios, George Androutsos, Maria Piagkou, Marilita M. Moschos

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In ancient Greek the term ὑπόφυσις meant literally something growing from below, the word being composed of the two elements hypo (Greek: ὑπό, below) and phyomai (φύομαι, grow). In ancient Greek medical literature we find this term with various meanings …