Applications of genomic medicine in endocrinology and post-genomic endocrine research

Constantine A. Stratakis

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In the mid 1980’s, two advances revolutionized Medicine in a way that is comparable only to some of the most important events in the approximately 3,000 years of its history. The first was the introduction of the concept of “positional cloning”, i.e. the idea that one can identify genes for human disease though knowing nothing or very little about their function…

Tracing the origin of the term “gene”

Theano D. Kontopoulou, Spyros G. Marketos

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A century has passed (1902 – 2002) since the Danish botanist and geneticist Wilhelm Ludwig Johannsen established the scientific term “gene”. The centenary of this biological term coincides with the 50th anniversary of the unraveling of the structure of DNA, the basic molecule of heredity …