Total parathyroidectomy with autotransplantation in patients with renal hyperparathyroidism: indications and surgical approach

Stavros Gourgiotis, Panagiotis Moustafellos, Charalabos Stratopoulos, Vasilis Vougas, Spiros Drakopoulos, Evangelos Hadjiyannakis

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OBJECTIVE: renal hyperparathyroidism (rH) is one of the most serious complications in long-term hemodialysis patients. the purpose of this retrospective study was the evaluation of the surgical indications, parathyroid histology, and the results of total parathyroidectomy with autotransplantation (Ptx+At) in patients with rH…

Minimally invasive parathyroidectomy in patients with previous neck surgery

Spiridon Dimas, Spiridon Michas, Ioannis Christakis, Christos Augoustis, Maria Alevizaki

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OBJECTIVE: Previous neck surgery (PNS) in patients with primary hyperparathyroidism (PHP) is considered as a contraindication for minimally invasive parathyroidectomy (MIP). The purpose of our study was to determine the effectiveness of MIP in such patients …

Calciphylaxis: a complication of end-stage renal disease improved by parathyroidectomy

John C. Maroulis, Constantinos Fourtounas, John G. Vlachojannis, Nikolaos Siasos, Dionysios Karavias, Dionysios Chartoumpekis, Ioannis Habeos

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A 43-year old Caucasian male with end-stage renal disease presented with painful skin lesions and high calcium phosphate product that did not respond to medical treatment. Skin biopsy confirmed the diagnosis of calciphylaxis. Urgent parathyroidectomy was performed and reĀ­sulted in decrease in the calcium phosphate product and improvement of his symptoms and signs …

Post-surgery severe hypocalcemia in primary hyperparathyroidism preoperatively treated with zoledronic acid

Salvatore Maria Corsello, Rosa Maria Paragliola, Pietro Locantore, Francesca Ingraudo, Maria Pia Ricciato, Carlo Antonio Rota, Paola Senes, Alfredo Pontecorvi

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Zoledronic acid is a newly FDA-approved bisphosphonate for the treatment of hypercalcemia of malignancy. Although the safety and efficacy of this drug in treating hypercalcemia associated with hyperparathyroidism have not yet been established in clinically controlled trials, its off-label use is not uncommon …

The history of the parathyroid glands

Ilias-Dimitrios Kafetzis, Antonis Diamantopoulos, Ioannis Christakis, Basileios Leoutsakos

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Greep in 1963 as well as Pang and Epple in 1980 advanced the view that the parathyroids originally appeared 100 million years ago, in the context of the evolutionary development of amphibians. This coincided with the transition of life from the calcium-rich marine environment to the terrestrial or the aquatic environments …