Smoking is a significant determinant of low serum vitamin D in young and middle-aged healthy males

Eva N. Kassi, Spiros Stavropoulos, Panayiotis Kokkoris, Antonis Galanos, Paraskevi Moutsatsou, Cleanthi Dimas, Athanasios Papatheodorou, Christos Zafeiris, George Lyritis

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OBJECTIVE: We aimed to determine the prevalence of 25(OH)D (D2 and D3 independently) inadequacy in healthy young/middle-aged men and to investigate its relationship with BMD, bone markers, demographic and lifestyle parameters such as age, BMI, smoking, alcohol consumption and dietary calcium intake …

Assessment of salivary free cortisol levels by liquid chromatography with tandem mass spectrometry (LC-MS/MS) in patients treated with mitotane

Cinzia Carrozza, Rosa Lapolla, Jacopo Gervasoni, Carlo Antonio Rota, Pietro Locantore, Alfredo Pontecorvi, Cecilia Zuppi, Silvia Persichilli

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OBJECTIVE: Mitotane is an adrenocytolytic agent used in adrenocortical carcinoma, inducing adrenal insufficiency, requiring replacement treatment. Such therapy is not easy to monitor because of mitotane interference. Salivary cortisol reflects a free fraction of plasma …