Increased leptin levels in preeclampsia: associations with BMI, estrogen and SHBG levels

Acromite Michael, Ziotopoulou Mary, Orlova Christine, Mantzoros Christos

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Leptin is secreted mainly by the white adipose tissue but is also synthesized in several non-adipose tissue organs including the placenta. Serum leptin levels are increased in normal pregnancies and are higher in preeclamptic than normal pregnant women. There is, however, a lack of empirical evidence of an independent association of serum leptin levels and preeclamsia …