Comments on gestational diabetes mellitus: from pathophysiology to clinical practice

Pavlos Poulakos, Gesthimani Mintziori, Efrosini Tsirou, Eleftheria Taousani, Dimitra Savvaki, Vikentia Harizopoulou, Dimitrios G. Goulis

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Gestational diabetes mellitus (GDM) is a topic of major interest, as it affects up to 16% of pregnant women and may lead to adverse pregnancy outcomes, which, however, are preventable by appropriate treatment. The aim of the present study was to discuss basic concepts and to critically appraise recent updates on practical issues …

Early metabolic defects following gestational diabetes in three ethnic groups of anti-GAD antibodies negative women with normal fasting glucose

Eleni Kousta, Natasha J. Lawrence, Ian F. Godsland, Anna Penny, Victor Anyaoku, Barbara A. Millauer, Stephen Robinson, Desmond G. Johnston, Mark I. McCarthy

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OBJECTIVE: To characterise early metabolic abnormalities and the impact of ethnicity following gestational diabetes mellitus (GDM). DESIGN: Women with a history of GDM belonging to three different ethnic groups were evaluated. Using the insulin-modified, frequently-sampled intravenous glucose tolerance test (FSIVGTT) and HOMA we studied 34 European …

Pre- and early post-partum adiponectin and Interleukin-1beta levels in women with and without gestational diabetes

Nikolaos Vitoratos, Georgios Valsamakis, George Mastorakos, Anastassios Boutsiadis, Nikolaos Salakos, Evagelia Kouskouni, George Creatsas

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OBJECTIVE: To investigate maternal serum adiponectin and Ιnterleukin-1beta (IL-1β) levels during the pre- and post-partum periods in pregnant women with and without Gestational Diabetes Mellitus (GDM). DESIGN: Thirty control pregnant Caucasian women without GDM and thirty Body Mass Index (BMI) and age-matched Caucasian women with GDM examined in the outpatient clinic between …