Male offspring of both diabetic parents have higher insulin resistance and serum leptin levels compared to those with one diabetic parent

Adeela Shahid, Khalid P. Lone, Sadia Saeed, Muhammad Arslan

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OBJECTIVE: We studied the influence of positive family history (FH) of type 2 diabetes mellitus (T2DM) in male offspring using multiple metabolic and endocrine parameters in order to assess whether one or more of these parameters can be used as indicators for T2DM development later in life. DESIGN: Fifty male subjects with one diabetic parent (ODP) and thirty with both diabetic parents …