Insulin action in morbid obesity: a focus on muscle and adipose tissue

Panayota Mitrou, Sotirios A. Raptis, George Dimitriadis

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The aim of this review is to summarize the mechanisms underlying insulin resistance in morbid obesity. Glucose regulation by insulin depends on the suppression of endogenous glucose production and stimulation of glucose disposal. In morbid obesity, glucose production by the liver is increased …

Muscle strength and bone in healthy women: effect of age and gonadal status

Cristiana Cipriani, Elisabetta Romagnoli, Vincenzo Carnevale, Ida Raso, Addolorata Scarpiello, Maurizio Angelozzi, Andrea Tancredi, Stefania Russo, Federica De Lucia, Jessica Pepe, Salvatore Minisola

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OBJECTIVE: The aim of this work was to examine the effects of age and menopause on muscle strength and on the muscle-bone interaction. DESIGN: One hundred ninety-four healthy women (mean age 49.8 ± 12.6 SD years) were assessed …