Novel Approaches to the Management of Graves` Ophthalmopathy

Luigi Bartalena, Maria Laura Tanda, Alessandra Medea, Claudio Marcocci, Aldo Pinchera

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Severe Graves’ ophthalmopathy constitutes a complex therapeutic challenge and treatment outcome often is not satisfactory. Established methods of treatment include high-dose glucocorticoids, orbital radiotherapy and orbital decompression. Recently, the use of intravenous glucocorticoids has been shown to provide more favorable results than oral glucocorticoids…

Insulin resistance, growth factors and cytokine levels in overweight women with breast cancer before and after chemotherapy

Eftychia Chala, Christos Manes, Helias Iliades, Georgios Skaragkas, Despina Mouratidou, Efthymios Kapantais

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OBJECTIVE: To evaluate insulin values, insulin resistance, growth factors and cytokine levels in women suffering from breast cancer and the effect of chemotherapy on these parameters. DESIGN: In a prospective study, glucose and insulin values were determined in ten previously undiagnosed diabetic postmenopausal women with stage IV breast cancer (hepatic metastases excluded) during an oral glucose tolerance test …