Non-alcoholic fatty liver disease in women with polycystic ovary syndrome: assessment of non-invasive indices predicting hepatic steatosis and fibrosis

Stergios A. Polyzos, Dimitrios G. Goulis, Jannis Kountouras, Gesthimani Mintziori, Panagiotis Chatzis, Efstathios Papadakis, Ilias Katsikis, Dimitrios Panidis

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OBJECTIVE: Insulin resistance contributes to the pathogenesis of both polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD). The main aim of the present study was the evaluation of non-invasive indices of hepatic steatosis and fibrosis in PCOS women with or without metabolic syndrome …

Lipid accumulation product is associated with metabolic syndrome in women with polycystic ovary syndrome

Djuro Macut, Ivana Božić Antić, Jelica Bjekić-Macut, Dimitrios Panidis, Konstantinos Tziomalos, Danijela Vojnović Milutinović, Olivera Stanojlović, Biljana Kastratović-Kotlica, Milan Petakov, Nataša Milić

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OBJECTIVE: There is a need for a simple and accurate method for the assessment of cardiovascular risk in polycystic ovary syndrome (PCOS). Lipid accumulation product (LAP) is based on the assessment of waist circumference and serum triglycerides that yield an estimation of lipid overaccumulation. We aimed to determine whether LAP is associated with metabolic syndrome (MetS) in Caucasian women with PCOS …