Laura Mihalache, Andreea Gherasim, Otilia Niță, Maria Christina Ungureanu, Sergiu Serghei Pădureanu, Radu Sebastian Gavril, Lidia Iuliana Arhire
Ghrelin is a gut peptide composed of 28 amino acids mostly secreted in the gastric fundus mucosa. It was isolated and described in 1999 by Kojima et al. and only three years later its specific receptor, GHSR1a, was also identified. Ghrelin, the endogenous ligand for the GH secretagogue receptor, is the only peripheral orexigenic hormone that activates the receptors to be found especially in the appetite center (hypothalamus and pituitary gland) …