Natalia Sirimi, Dimitrios G. Goulis
Obesity, the most common metabolic disorder, concerns, among others, women of reproductive age and, when it occurs before or during pregnancy, constitutes a major risk factor for both maternal and fetal complications. The complications of obesity in a prospective mother include subfertility, miscarriage, thrombo-embolism, hypertensive disorders …
Marià Alemany
The clairvoyant early implication of sex hormones in the characterization of the metabolic syndrome (MS) was detected early, and in accordance with the well-known sex-related main patterns of fat deposition in obesity: gynoid and android …
Filippo Ceccato, Mattia Barbot, Marialuisa Zilio, Sergio Ferasin, Paola De Lazzari, Laura Lizzul, Marco Boscaro and Carla Scaroni
Objective: Measurement of cortisol levels in saliva is a marker of free hormone. How salivary cortisol rhythm is affected by age, gender, the metabolic syndrome and estrogen-progestin therapy was evaluated in a community sample of adults …
Stergios A. Polyzos, Dimitrios G. Goulis, Jannis Kountouras, Gesthimani Mintziori, Panagiotis Chatzis, Efstathios Papadakis, Ilias Katsikis, Dimitrios Panidis
OBJECTIVE: Insulin resistance contributes to the pathogenesis of both polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD). The main aim of the present study was the evaluation of non-invasive indices of hepatic steatosis and fibrosis in PCOS women with or without metabolic syndrome …
Thomas JG. Chambers, Richard A. Anderson
Obesity in men of reproductive age is globally on the increase. There is clear evidence from epidemiological studies that obesity impacts negatively on male fertility; it is associated with hypogonadism, although it is less consistently linked to impaired spermatogenesis and tests of sperm function, including DNA fragmentation …
Konstantinos Makrilakis, Sofia Grammatikou, Stavros Liatis, Meropi Kontogianni, Despoina Perrea, Charilaos Dimosthenopoulos, Kalliopi-Anna Poulia, Nicholas Katsilambros
OBJECTIVE: The aim of the present study was to evaluate the effectiveness of a non-intensive, community-based, lifestyle intervention program on the prevalence of metabolic syndrome (MS), in individuals at high risk for development of type 2 diabetes …
Panagiota Pervanidou, Giorgos Chouliaras, Athanassios Akalestos, Despoina Bastaki, Filia Apostolakou, Ioannis Papassotiriou, George P. Chrousos
OBJECTIVE: Childhood obesity and the Metabolic Syndrome (MetS) are associated with an increased risk for early onset endothelial dysfunction and atherosclerosis. Placental growth factor (PlGF), a member of the vascular endothelial growth factor family, plays an important role in atherosclerosis by stimulating angiogenesis …
Stergios A. Polyzos, Jannis Kountouras, Agathocles Tsatsoulis, Efthimia Zafeiriadou, Evangelia Katsiki, Kalliopi Patsiaoura, Christos Zavos, Vasiliki V. Anastasiadou, Aristidis Slavakis
OBJECTIVE: The evaluation of serum sex steroids and sex hormone-binding globulin (SHBG) levels in postmenopausal women with nonalcoholic fatty liver disease (NAFLD) and their association to the disease severity. DESIGN: Twenty-two postmenopausal women with biopsy-proven NAFLD …
Djuro Macut, Ivana Božić Antić, Jelica Bjekić-Macut, Dimitrios Panidis, Konstantinos Tziomalos, Danijela Vojnović Milutinović, Olivera Stanojlović, Biljana Kastratović-Kotlica, Milan Petakov, Nataša Milić
OBJECTIVE: There is a need for a simple and accurate method for the assessment of cardiovascular risk in polycystic ovary syndrome (PCOS). Lipid accumulation product (LAP) is based on the assessment of waist circumference and serum triglycerides that yield an estimation of lipid overaccumulation. We aimed to determine whether LAP is associated with metabolic syndrome (MetS) in Caucasian women with PCOS …
Giovanni Corona, Silvia Bianchini, Alessandra Sforza, Linda Vignozzi, Mario Maggi
There is evidence demonstrating that sexual complaints represent the most specific symptoms associated with late onset hypogonadism, while central obesity is the most specific sign. In obese men, hypogonadism can further worsen the metabolic profile and increase abdominal fat …
Yongbo Kang, Yue Cai
Obesity is a major public health issue as it is causally associated with several chronic disorders, including type-2 diabetes, cerebrovascular disease (CVD), and cancer. In the United States and other countries worldwide, the obesity epidemic has drastically impacted the status of health of millions as well as healthcare costs. Aside from poor diet, hygiene, and genetics, there are many other factors thought to play an important role in the emergence of obesity …
Mahin Hashemipour, Roya Kelishadi, Javad Shapouri, Nizal Sarrafzadegan, Masoud Amini, Naser Tavakoli, Ahmad Movahedian-Attar, Parisa Mirmoghtadaee, Parinaz Poursafa
OBJECTIVE: Zinc, an essential trace element and a component of many enzymes, is involved in the synthesis, storage and release of insulin. The aim of the present study was to assess the effect of zinc supplementation on insulin resistance and components of the metabolic syndrome in prepubertal obese children. DESIGN: This triple-masked …
Christos G. Verras, Georgios A. Christou, Yannis V. Simos, George D. Ayiomamitis, Andreas J. Melidonis, Dimitrios N. Kiortsis
OBJECTIVE: The elucidation of the changes of fetuin-A in the context of bariatric surgery. DESIGN: Twenty obese patients (8 males, 12 females; body mass index = 42.5±3.4 kg/m2) were studied at baseline and 6 months after bariatric surgery. RESULTS: Serum fetuin-A levels did not differ with regard to the presence …