Insulin action in morbid obesity: a focus on muscle and adipose tissue

Panayota Mitrou, Sotirios A. Raptis, George Dimitriadis

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The aim of this review is to summarize the mechanisms underlying insulin resistance in morbid obesity. Glucose regulation by insulin depends on the suppression of endogenous glucose production and stimulation of glucose disposal. In morbid obesity, glucose production by the liver is increased …

High rates of obesity prevalence in adults living in Central Greece: Data from the ARGOS Study

George N. Koukoulis, Christina Sakka, Fotis Katsaros, Maria Goutou, Sofia Tsirona, Efthimia Tsiapali, Aristea Piterou, Ioannis Stefanidis, Nikolaos Stathakis

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OBJECTIVE: To investigate the prevalence of obesity in adults of a large region of Central Greece. DESIGN: The target group was adults aged 18 to 79 years who were residents of the region of Thessaly for at least one year. A sample of 852 individuals stratified for sex and age were included. Each subject underwent a thorough physical examination and body mass index …