Effect of weight loss with or without orlistat treatment on adipocytokines, inflammation, and oxidative markers in obese women

Maria Bougoulia, Athanassios Triantos, George Koliakos

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OBJECT IVE: T he aim of this study was to evaluate the levels of adipose tissue related hormones, cytokines, and antioxidative substances in obese women before and after intervention with diet alone or with diet plus an inhibitor of gastrointestinental lipase-orlistat…

Plasma Interleukin-6 levels, glutathione peroxidase and isoprostane in obese women before and after weight loss. Association with cardiovascular risk factors

Maria Bougoulia, Athanassios Triantos, George Koliakos

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OBJECTIVE: To evaluate the levels of Interleukin-6 (IL-6), glutathione peroxidase and iso­prostane in obese women and their association with markers of cardiovascular risk factors before and after weight loss. DESIGN: 36 healthy obese women of reproductive age (group A: age (mean ±SD) 35.4 ± 9.2 years, Body Mass Index (BMI) 38.5±7 kg/m2) and 30 healthy, normal weight women …

Effect of hyperglycemia and hyperinsulinemia on glutathione peroxidase activity in non-obese women with polycystic ovary syndrome

Ana Savic-Radojevic, Ivana Bozic Antic, Vesna Coric, Jelica Bjekic-Macut, Tanja Radic, Milos Zarkovic, Tatjana Djukic, Marija Pljesa-Ercegovac, Dimitrios Panidis, Ilias Katsikis, Tatjana Simic, Djuro Macut

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OBJECTIVE: In order to gain deeper insight into molecular mechanisms underlying oxidative stress (OS) and its relation to insulin resistance and hyperandrogenemia, plasma markers of OS and antioxidant glutathione-peroxidase (GPX) activity were studied in non-obese polycystic ovary syndrome (PCOS) women via the oral glucose tolerance test …