The AGT and the GNB3 polymorphisms and insulin resistance in prehypertension

Christos Maniotis, Klio Chantziara, Panagiotis Kokkoris, Dimitrios Papadogiannis, Constantinos Andreou, Constantinos Tsioufis, Georgios Vaiopoulos, Christodoulos Stefanadis

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OBJECTIVE: This study surveyed the frequencies of single nucleotide polymorphisms (SNPs) M235T AGT and C825T GNB3, and their association with insulin resistance, other biochemical markers and qualitative variables in subjects with high normal blood pressure and/or prehypertension in the Greek population …

Genetic diagnosis of idiopathic hypogonadotrophic hypogonadism: a new point mutation in the KAL2 gene

Carmen Entrala-Bernal, Cristina Montes-Castillo, Maria Jesus Alvarez-Cubero, Carmen Gutiérrez-Alcántara, Francisco Fernandez-Rosado, Esther Martinez-Espίn, Carolina Sánchez-Malo, Piedad Santiago-Fernández

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Kallmann Syndrome (KS) is a genetic disease of embryonic development which is characterized by the association of hypogonadotropic hypogonadism (HH) due to a deficit of the gonadotropin-releasing hormone (GnRH) and a hypo/anosmia (including a hypoplasia of the nasal sulcus and agenesis of the olfactory bulbs) …