Themistoklis Mikos1, Konstantinos Pantazis1, Dimitrios G. Goulis1, Nikolaos Maglaveras2, John N. Bontis1, John Papadimas1 1Unit of Reproductive Endocrinology, 1st Department of Obstetrics & Gynaecology, and 2Laboratory of Medical Informatics, Aristotle University of Thessaloniki, Thessaloniki, Greece Abstract OBJECTIVE: Data Mining is a relatively new field of Medical Informatics. The aim of this study was to compare Read More
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Thyroid carcinoma in children and adolescents. Presentation, clinical course, and outcome of therapy in 23 children and adolescents in Northern Greece
Kalliopi Pazaitou-Panayiotou1, Athina Kaprara1, Maria Boudina1, Eleni Georgiou1, Apostolos Drimonitis1, Ekaterini Raptou2, Grammati Galaktidou3, Iraklis Vainas1 1Department of Endocrinology-Endocrine Oncology, 2Department of Nuclear Medicine, 3Research Center, Theagenion Cancer Hospital, Thessaloniki, Greece Abstract OBJECTIVE: To define clinical presentation, surgical complications, follow-up characteristics, and survival of 23 children and adolescents with thyroid carcinoma. DESIGN: Retrospective analysis of Read More
Data Mining: A New Technique In Medical Research
Eirini Papageorgiou,1 Ioanna Kotsioni,1 Athena Linos2 1Institute of Preventive Medicine, Environmental and Occupational Health (Prolepsis), 2Department of Hygiene and Epidemiology, Medical School, University of Athens, Athens, Greece This issue hosts an article that discusses the application of Data mining techniques to the treatment of infertile men with azoospermia, and compares this procedure of categorisation into Read More
Endocrine manifestations in DiGeorge and other microdeletion syndromes related to 22q11.2
Sofia Kitsiou-Tzeli, Aggeliki Kolialexi, Ariadni Mavrou Department of Medical Genetics, Athens University, Agia Sophia Children's Hospital, Athens, Greece INTRODUCTION Microdeletions, translocations or other rearrangements of chromosomal region 22q11.2 have been reported in association with >80 different birth defects and malformations occurring in many combinations and with widely differing severity.1 Furthermore, a tendency to report atypical Read More
Obesity in Childhood and Adolescence: a review in the interface between adipocyte physiology and clinical challenges
Antje Körner,1 Susann Blüher,1 Thomas Kapellen,1 Ante Garten,1 Jürgen Klammt,1 Jürgen Kratzsch,2 Wieland Kiess1 1Hospital for Children and Adolescents, 2Institute of Laboratory Medicine, Clinical Chemistry & Molecular Diagnostics, University of Leipzig, Leipzig, Germany Abstract Body weight is regulated by a feedback loop in which peripheral signals report nutritional information to an integratory center in the Read More
Symptomatic pheochromocytoma with normal urinary catecholamine metabolites
Dimitra Zianni1, Marinella Tzanela1, Serafim Klimopoulos2, N.C. Thalassinos1 Department of Endocrinology Diabetes and Metabolism1 and 2nd Department of Surgery2, Evangelismos Hospital, Athens, Greece Abstract A 61-year old female presented with paroxysmal hypertension and a 4.5cm left adrenal mass on CT scan. Repeated measurements of 24-hour urinary fractionated metanephrines, total catecholamines and vanillylmandelic acid (VMA) were Read More
Familial paraganglioma: A novel presentation of a case and response to therapy with radiolabelled MIBG
Justin K. Lawrence1, Eamonn R. Maher2, Richard Sheaves3, Ashley B. Grossman1 1Department of Endocrinology, St. Bartholomew's & the Royal London School of Medicine and Dentistry, London, UK; 2Section of Medical and Molecular Genetics, Department of Paediatrics and Child Health, School of Medicine, University of Birmingham and West Midlands Genetics Service, Birmingham, UK; and 3Centre for Read More
The serum triiodothyronine to thyroxine (T3/T4) ratio in various thyroid disorders and after Levothyroxine replacement therapy
A. Mortoglou, H. Candiloros Department of Endocrinology, Diabetes and Metabolism, Athens Medical Centre Hospital, Athens, Greece Abstract In order to examine the significance of differences in the triiodothyronine/thyroxine (T3/T4) ratio in the achievement of euthyroidism and in different thyroidal diseases, we studied 1050 subjects: 233 were euthyroid (Eu), 239 hypothyroid (Hypo) with initial TSH levels Read More
Factors associated with body mass index in adults from Northern Greece
Themistoklis Tzotzas1, Theodoros Konstantinidis2, Maria Bougoulia1, Gerasimos E. Krassas1 1Department of Endocrinology, Diabetes and Metabolism, Panagia General Hospital, Thessaloniki, Greece, 2Department of Hygiene and Statistics, Dimokritio University of Thrace, Thrace-Greece Abstract The aim of this large scale epidemiological cross-sectional study was to investigate potential factors, such as age, gender, socioeconomic status (measured as educational level Read More
Histopathology of Thyroid Tumors. An Overview
Chrisoula D. Scopa Dept. of Pathology, University of Patras, School of Health Sciences, Faculty of Medicine, Patras, Greece INTRODUCTION Thyroid cancer accounts for approximately 1% of total cancer cases in developed countries. It affects all age groups, although it is rare in children. Thyroid tumors are more frequent in women than in men. Despite their Read More