Targeting the osteoblast: approved and experimental anabolic agents for the treatment of osteoporosis

Konstantinos A. Toulis, Athanasios D. Anastasilakis, Stergios A. Polyzos, Polyzois Makras

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Targeting osteoblast may be the means of effectively improving both bone quality and mass, thus offering an intriguing alternative in the treatment of osteoporosis. Aside from injectable parathyroid hormone (PTH) and its novel preparations, PTH-related peptide (PTHrP), calcilytics …

Sequential treatment with teriparatide and strontium ranelate in a postmenopausal woman with atypical femoral fractures after long-term bisphosphonate administration

Kalliopi Lampropoulou-Adamidou, Symeon Tournis, Alexia Balanika, Ioulia Antoniou, Ioannis P. Stathopoulos, Christos Baltas, Ioannis K. Triantafillopoulos, Nikolaos A. Papaioannou

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OBJECTIVE: Despite the existence of numerous case series, no evidenced-based medical management for atypical fractures associated with bisphosphonate (BP) treatment has been established. DESIGN: We report the outcome of teriparatide (TRP) administration followed …

Case Report: Teriparatide treatment in a case of severe pregnancy -and lactation- associated osteoporosis

Kalliopi Lampropoulou-Adamidou, George Trovas, Ioannis P. Stathopoulos, Nikolaos A. Papaioannou

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OBJECTIVE: Pregnancy- and lactation-associated osteoporosis (PLO) is an uncommon disease. The majority of cases are seen in the third trimester or early post-partum in primagravid women and the prominent clinical feature of PLO is severe and prolonged back pain and height loss. The prevalence and aetiology of this disorder …