Eleni Kousta, Asteroula Papathanasiou, Nicos Skordis
There have been considerable advances concerning understanding of the early and later stages of ovarian development; a number of genes have been implicated and their mutations have been associated with developmental abnormalities …
Ayla Güven, Ayşe Nurcan Cebeci, Suna Hancili
OBJECTIVE: Congenital adrenal hyperplasia (CAH) can be complicated by central precocious puberty (CPP) in children, which may compromise final height. We aimed to evaluate the effect of gonadotropin-releasing hormone analog (GnRHa) therapy on growth in children with CAH …
Eleni-Magdalini Kyritsi, Georgia Koltsida, Ioanna Farakla, Aikaterini Papanikolaou, Elena Critselis, Emilia Mantzou, Emmanouil Zoumakis, Gerasimos Kolaitis, George P. Chrousos, Evangelia Charmandari
OBJECTIVE: Carriers of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21-OHD) demonstrate increased secretion of cortisol precursors following ACTH stimulation, suggestive of impaired cortisol production and compensatory increases in hypothalamic corticotropin-releasing hormone (CRH) secretion. Both cortisol and CRH have behavioral effects, and hypothalamic CRH hypersecretion has been associated with chronic states of anxiety and depression …
Neoklis A. Georgopoulos, George A. Vagenakis, Apostolos L. Pierris
In an Orphic account of the constitutive mythology of the Eleusinian Mysteries, there occurs the relation of a remarkable tale of sacred obscenity. The Baubo affair is pivotal for a more in-depth understanding of the symbolism involved in the most awesome mysteric cult of the ancient Greek world …