Hypokalemic paralysis following administration of intravenous methylprednisolone in a patient with Graves’ thyrotoxicosis and ophthalmopathy

Stelios Tigas, Petros Papachilleos, Nikolaos Ligkros, Maria Andrikoula, Agathocles Tsatsoulis

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Glucocorticoids are commonly used in the treatment of patients with thyroid disorders, in particular Graves’ ophthalmopathy. Thyrotoxic hypokalemic periodic paralysis (TPP) is an infrequent but potentially serious condition characterised by recurrent episodes of weakness associated with hypokalemia …

Thyrotoxic hypokalemic periodic paralysis in a Turkish patient presenting with a U wave on ECG

Emre Gezer, Banu Şarer Yurekli, Gokçen Unal Kocabas

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Hypokalemic periodic paralysis (HPP) is a rare neuromuscular disorder caused by dysfunction of the ion channels in red muscle cells and which is characterized by painless episodes of muscle weakness generally after strenuous exertion or a high-carbohydrate meal …

A novel CYP11B1 mutation in a Turkish patient with 11β-hydroxylase deficiency: An association with the severe hypokalemia leading to rhabdomyolysis

Banu Sarer Yurekli, Nilufer Ozdemir Kutbay, Huseyin Onay, Ilgin Yildirim Simsir, Gokcen Unal Kocabas, Mehmet Erdogan, Sevki Cetinkalp, Gokhan Ozgen, Fusun Saygili

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Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder caused by the loss of one of five steroidogenic enzymes affecting cortisol synthesis. Deficiency of 21-hydroxylase is the most common cause of CAH, accounting for more than 90% of all cases; it is followed in frequency by 11β-hydroxylase deficiency (11βOHD), reported to be between 3% and 5% of cases …