Non tumoral hyperserotoninaemia responsive to octreotide due to dual polymorphism in UGT1A1 and UGT1A6

Anna Maladaki, Maria P. Yavropoulou, Kalliopi Kotsa, Theoni Tranga, Stelios Ventis, John G. Yovos

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Gilbert’s syndrome is a common inherited metabolic disorder, caused by genetic aberration in the enzyme UDP-glucuronosyl-transferase 1A1 that leads to reduced glucuronidation of bilirubin. Recent advances in molecular genetics have frequently reported the concurrence of dual genetic …