Galectin-3 as a marker distinguishing functioning from silent corticotroph adenomas

Eleni Thodou, Theodore Argyrakos, George Kontogeorgos

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OBJECTIVE: Galectin-3 (Gal-3) belongs to the family of carbohydrate-binding proteins with high affinity for galactoside and is involved in many biological processes including cell growth and differentiation, cell adhesion, tumor progression, apoptosis and metastasis. The aim of this study was to disclose differences in the expression of Gal-3 in silent …