Marinella Tzanela, Marieta Christoforaki, Lida Papastathopoulou, Dimitra Vassiliadi, Effie Botoula, Panagiotis Trivizas, Nikos C. Thalassinos Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece Abstract Objective: Post-treatment monitoring of acromegalic patients is a matter of controversy, as discrepancies between GH and IGF-I levels have been reported. The aim of our study was to evaluate Read More
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Effects of GH and IGF-I on the in vitro maturation of mouse oocytes
Erasmia Kiapekou1, Dimitris Loutradis2, Peter Drakakis2, Evangelia Zapanti1, George Mastorakos3, Aristidis Antsaklis2 11st Endocrine Section, Alexandra Hospital, Athens, Greece, 21st Department of Obstetrics and Gynaecology, Alexandra Hospital, Athens university medical school, Athens, Greece, 3Endocrine Unit, 2nd Department of Obstetrics and Gynaecology, Aretaion Hospital, Athens university medical school, Athens, Greece Abstract Objective: A number of hormones Read More
Hypoparathyroidism in a patient presenting with severe myopathy and skin rash. Case report and review of the literature
Vassiliki Syriou, Asimina Kolitsa, Lamprini Pantazi, Dimitrios Pikazis Department of Pathophysiology Laiko Hospital, University of Athens, School of Medicine, Athens, Greece Abstract A 47-year old man with idiopathic hypoparathyroidism (IHP), presented as severe myopathy and skin rash is described. The serum muscle enzymes were increased. After treatment with calcium and vitamin D, the clinical condition Read More
A case of a prolactinoma resistant to dopamine agonists
Irene Vourliotaki1, Ingrid Elizabeth Bonapart1, Catherine Stamataki1, Eva-Maria Tsapakis2, Catherine Saridaki1 1Department of Endocrinology and Metabolism, Venizelio General Hospital, Iraklion, Crete, Greece, 2Institute of Psychiatry, London, UK Abstract Dopamine agonists are the drugs of choice in the treatment of prolactinomas, the most common type of pituitary adenomas. However, up to 25% of prolactinomas do not Read More
Hypophosphataemic osteomalacia due to de Toni-Debre-Fanconi syndrome in a 19-year old girl
Tasoula Tsilchorozidou, John G Yovos Division of Endocrinology, Diabetes and Metabolism, AHEPA University Hospital, Thessaloniki, Greece Abstract Osteomalacia associated with adult onset Fanconi syndrome is thought to result from hypophosphataemia due to renal phosphate loss and relative 1,25-dihydroxyvitamin D3 deficiency. In this disorder, the impaired renal phosphate uptake occurs as part of a generalized tubular Read More
On the centenary of the term
Effie Poulakou-Rebelakou, Costas Tsiamis, Spyros G. Marketos History of Medicine, Athens University, Medical School INTRODUCTION In June of 2005 the term hormone completed a life span of one century. The word that Ernest Henry Starling included in one of his four lectures to the Royal Society of Physicians of London, given in June 1905, definitively Read More
Obesity and renal disease: A possible role of leptin
Dafni-Kalliopi Papafragkaki1, George Tolis2 1Department of Internal Medicine Advocate Illinois Masonic Medical Center, Chicago, IL, 60657, USA, 2Division of Endocrinology and Metabolism Hippokrateion Hospital, Athens, 115 27, Greece Abstract Obesity is one of the most frequently encountered medical problems of our time. Among the complications of this pathologic entity, renal disease is an important issue Read More
Intramuscular administration of ACTH1-24 vs. 24-hour blood sampling in the assessment of adrenocortical function
Salvatore Alesci1, Ioannis Ilias2,3, Emmanuil Souvatzoglou3, Alan G. Harris4, Philip W. Gold1, Alejandro R. Ayala3, George P. Chrousos3 1Clinical Neuroendocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892-1284 USA, 2Department of Pharmacology, Medical School, University of Patras, Rion-Patras, 265 04, Greece, 3Reproductive Biology and Medicine Branch, National Institute of Child Read More
TSH and thyroid hormones concentrations in patients with hypothyroidism receiving replacement therapy with L-thyroxine alone or in combination with L-triiodothyronine
Valentin V. Fadeyev, Tatiana B. Morgunova, Julia P. Sytch, Galina A. Melnichenko Department of Endocrinology of Moscow Medical Academy, Moscow, 119992, Russia Abstract The aim of this study was to evaluate parameters of thyroid function in patients with primary hypothyroidism receiving either monotherapy with L-T4 or combination L-T4+L-T3. Fifty-eight women with primary hypothyroidism receiving L-T4 Read More
Reassessment of combined LT4 and LT3 treatment for hypothyroidism: the prospects for slow-release T3 preparations
Leonidas H. Duntas Endocrine Unit, Evgenidion Hospital, Athens University Medical School, Athens, 115 27, Greece "Do not draw conclusions which arise from logic alone, but also from practical demonstration"Hippocrates The introduction of synthetic levothyroxine (LT4) in the late 60's for treatment of hypothyroidism radically changed the therapeutic approach for patients with thyroid failure, enabling Read More